Testicular autoimmunity : a cause of male infertility /: a cause of male infertility. (2017)

• Record Type: Book
• Further Information: Note: Masahiro Itoh.
• Authors: Itoh, Masahiro
• Contents: Preface; Acknowledgments; Contents; Abbreviations; 1: Biological Background of Testicular Autoimmunity; 1.1 Introduction; 1.2 Developmental Phase Differences Between Reproductive and Lymphoid Organs; 1.3 Evolution of the Reproductive and Immune Systems; 1.4 Offensive Attack on Germ Cells by Acquired (Adoptive) Immunity; 1.5 Harsh Immunological Fate of Male Haploid Germ Cells (Spermatids/Spermatozoa); 1.6 Endocrinological Relation Between the Testicular and Immune Functions; References; 2: Microcircumstance for Induction and Prevention of Testicular Autoimmunity; 2.1 Introduction. 2.2 Autoimmunogenicity of Spermatids and Spermatozoa2.3 Protection of Autoimmunogenic Spermatids and Spermatozoa by the Blood-Testis Barrier (BTB); 2.4 Protection of Autoimmunogenic Spermatids and Spermatozoa by Various Local Elements Other Than the BTB; 2.5 Cell Populations Involved in the Testicular Immunoregulation; 2.5.1 Sertoli Cells; 2.5.2 Leydig Cells; 2.5.3 Testicular Leukocytes; 2.5.3.1 Macrophages; 2.5.3.2 Dendritic Cells; 2.5.3.3 Lymphocytes; 2.5.3.4 Other Leukocyte Populations; 2.5.4 Peritubular Myoid Cells and Basal Lamina; 2.5.5 Blood Capillary Endothelium. 2.5.6 Lymphatic Capillary Endothelium2.5.7 Testicular Germ Cells (TGC); 2.5.8 Seminal Plasma; 2.6 Resistance to Inflammatory Cell Responses of Various Types in the Testis; 2.6.1 Resistance to Rejection of Allografts in the Testis; 2.6.2 Spontaneous Occurrence of Vasculitis-Like Lesions in the Male Reproductive System; 2.6.3 Spermatic Granulomata by Local Trauma; 2.6.4 Spermatic Granulomata by Testosterone Treatment; 2.6.5 Reproductive Inflammation by Estrogen Treatment; 2.6.6 Reproductive Inflammation by Intravenous Administration of Bordetella pertussis (BP). 2.6.7 Spontaneous Infiltration of Eosinophils and Macrophages in Reproductive Tissues of Congenitally Lymph Node-ƯLacked Mice2.6.8 Multiple Organ-Localized Autoimmunity; 2.6.9 Resistance to Rejection of Transplanted Allogeneic and Xenogeneic Testis; 2.6.10 Successful Transplantation of Allografts and Xenografts by Co-transplantation with Sertoli Cells; 2.6.11 Successful Transplantation of Xenogeneic Spermatogenesis into the Recipient Testis; 2.6.12 Immune Tolerance Induced by Intratesticular Antigen Priming; 2.7 Five-Phased Immunoregulatory Barriers in the Testis. 2.8 Immunological Fragility of the Testicular Microcircumstance2.8.1 Regional Differences in the Integrity of the Immunological Shield by the BTB; 2.8.2 Pro-inflammatory Cytokines in the Testis Under Normal Condition; 2.8.3 Specific Localization of Immune Cells in the Testis Under Normal Condition; 2.8.4 Infiltration of Macrophages into the Testis in Secondary Biliary Cholestasis; 2.8.5 Mononuclear Cell Responses to Primary Testicular Cancer; 2.8.6 Frequent Involvement of Lymphocytic Leukemia in the Testis; 2.8.7 Natural Autoantibodies to Testicular Antigens.
• Publisher Details: Tokyo, Japan : Springer
• Publication Date: 2017
• Extent: 1 online resource
• Subjects: 612.6/14; 616.6921; Human reproduction -- Immunological aspects; Testis -- Immunology; MEDICAL -- Physiology; SCIENCE -- Life Sciences -- Human Anatomy & Physiology; Human reproduction -- Immunological aspects; Medicine & Public Health; Urology; Reproductive Medicine; Immunology; Reproduction -- immunology; Testis -- immunology; Electronic books; Electronic book
• Languages: English
• ISBNs: 9784431544609; 4431544607
• Related ISBNs: 9784431544593; 4431544593
• Notes: Note: Includes bibliographical references.; Note: Online resource; title from PDF title page (SpringerLink, viewed August 15, 2017).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.