COPD : heterogeneity and personalized treatment /: heterogeneity and personalized treatment. (2017)

• Record Type: Book
• Further Information: Note: Sang-Do Lee, editor.
• Editors: Lee, Sang-Do
• Contents: ""Preface""; ""Contents""; ""Part I: Overview""; ""1: Definition and Epidemiology of COPD""; "" Definition of COPD""; "" Epidemiology of COPD""; "" Prevalence""; "" Incidence""; "" Mortality""; "" Economic and Social Burden""; ""References""; ""2: Risk Factors: Factors That Influence Disease Development and Progression""; "" Genes""; "" Gender""; "" Lung Growth and Development""; "" Exposure to Particles""; "" Cigarette Smoking""; "" Occupational Exposures to Dusts, Chemical Agents, Fumes""; "" Indoor Air Pollution""; "" Outdoor Air Pollution""; "" Socioeconomic Status"" "" Asthma/Bronchial Hyperactivity"""" Infections""; ""References""; ""3: Pathology of Chronic Obstructive Pulmonary Diseases""; "" Introduction""; "" Lung Volumes in Lung Stereology""; "" Normal Lung""; "" Overall Structure""; "" Alveolar Tissue""; "" Small Airways""; "" Lung Cellular Composition""; "" Lung Growth""; "" Aged Lung""; "" COPD""; "" Chronic Bronchitis""; "" Small Airways""; "" Emphysema""; "" Quantification of Emphysema""; "" Microscopic Assessments of Emphysema""; "" Other Forms of Emphysema""; "" Involvement of Cellular Compartments in Emphysema"" "" Physiologicalâ#x80;#x93;Pathological Correlations"""" Pulmonary Vascular Structure and Function""; ""References""; ""4: Pathogenesis of COPD""; "" COPD Is an Inflammatory Disease""; "" Inflammatory Cells in COPD""; "" Airway Epithelial Cells""; "" Alveolar Macrophages""; "" Neutrophils""; "" Dendritic Cells""; "" Lymphocytes""; "" Other Cells""; "" Inflammatory Mediators in COPD""; "" Pathogenesis of Emphysema""; "" Protease-Antiprotease Imbalance in the Pathogenesis of COPD""; "" Protease-Antiprotease Imbalance in α1-Antitrypsin Deficiency"" "" Protease-Antiprotease Imbalance in COPD Without Antitrypsin Deficiency"""" Oxidative Stress in the Pathogenesis of COPD""; "" Physiological Roles of Radical Species""; "" Oxidative Stress in the Pathogenesis of COPD""; "" Cell Death and Impaired Repair in COPD""; "" Other Pathogenetic Mechanism of Emphysema""; "" Accelerated Aging""; "" Autoimmunity and COPD""; "" Epigenetic Changes in COPD Development""; "" Pathogenesis of Airway Obstruction""; "" Infiltration of Inflammatory Cells in Small Airways""; "" Mucus Hypersecretion""; "" Airway Remodeling"" "" Unanswered Question""""References""; ""Part II: Assessment""; ""5: Pathophysiology of COPD""; "" Mucus Hypersecretion and Ciliary Dysfunction""; "" Airflow Obstruction""; "" Hyperinflation""; "" Abnormality of Gas Exchange""; "" Pulmonary Arterial Hypertension""; "" Pathophysiology of COPD Exacerbation""; ""References""; ""6: Diagnosis and Assessment of COPD""; "" Introduction""; "" Diagnosis""; "" Symptoms""; "" Medical History""; "" Physical Examination""; "" Introduction to Pulmonary Function Testing""; "" Spirometry""; "" Lung Volumes""
• Publisher Details: Berlin, Germany : Springer
• Publication Date: 2017
• Extent: 1 online resource
• Subjects: 616.2/4; Lungs -- Diseases, Obstructive; HEALTH & FITNESS -- Diseases -- General; MEDICAL -- Clinical Medicine; MEDICAL -- Diseases; MEDICAL -- Evidence-Based Medicine; MEDICAL -- Internal Medicine; Lungs -- Diseases, Obstructive; Pulmonary Disease, Chronic Obstructive -- etiology; Genetic Heterogeneity; Precision Medicine; Pulmonary Disease, Chronic Obstructive -- therapy; Fulltext; Internet Resources
• Languages: English
• ISBNs: 9783662471784; 3662471787; 3662471779; 9783662471777
• Related ISBNs: 9783662471777
• Notes: Note: Includes bibliographical references and index.; Note: Online resource; title from PDF title page (SpringerLink, viewed October 19, 2017).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.