Understanding kidney diseases. (2016)

• Record Type: Book
• Further Information: Note: Hugh Rayner, Mark Thomas and David Milford.
• Authors: Rayner, Hugh; Thomas, Mark; Milford, David
• Contents: Introduction -- The purpose of the book -- understanding the natural history of kidney disease -- how displaying a GFR history is a fundamental part of the clinical assessment of kidney diseases -- how the eGFR graph is used to inform patients and plan treatment.-principles but not details of treatment -- The basics of creatinine measurement and eGFR equations in adults -- Simple guide to the classification of AKI, AKD and CKD -- Stages of CKD -- including proteinuria -- The meaning of 'stability' in an eGFR graph -- variation over time -- Cases -- Section 1: Acute kidney injury -- changes over 50% drop, assuming no asymmetry) -- Recurrent AKI leading to CKD -- Section 2: AKD -- changes>48 hours 3months -- Patterns of progression -- Linear and Non-linear -- Monitoring response to treatment -- e.g. immunosuppression for GN, BP control in malignant hypertension -- Section 4: CKD -- changes over years -- non-progressive (stable) CKD -- e.g. obstructive uropathy -- progressive CKD -- e.g. transplant nephropathy, lithium nephrotoxicity, role of proteinuria as risk marker -- Use of graphs to plan future renal replacement therapy -- e.g. linear progression in ADPKD -- Section 5: Acute-on-chronic kidney disease -- Chronic slowly progressive diabetic nephropathy with superimposed acute pathology, e.g. response to ACEI/ARB, contrast nephropathy, glomerulonephritis, interstitial nephritis -- Transplant rejection -- Pregnancy in women with CKD -- Section 6: Nephrotic syndrome -- GFR, serum albumin and urinary PCR graphs -- use to monitor treatment and relapses, and to plan treatment -- Section 7: Other graphs -- 24 hour BP measurement -- importance of nocturnal dip and timing of antihypertensives in CKD care -- Diabetes mellitus -- HbA1c -- colour coding as patient education tool; role of glucose control in preventing diabetic nephropathy (but no impact once CKD established) -- Serum free light chains and myeloma kidney/light chain nephropathy/immune GN -- Conclusions -- eGFR graphs -- an essential tool in patient assessment which tells the story of kidney disease -- The role of graphs (eGFR, 24 hour BP, and HbA1c) in patient education and support of self-management -- Role of eGFR graphs in systematic CKD surveillance by renal units and pathology labs -- evidence of benefit.
• Publisher Details: Cham : Springer Science and Business Media
• Publication Date: 2016
• Extent: 1 online resource
• Subjects: 616.61; Kidneys -- Diseases; Medicine; Diabetes; Nephrology; HEALTH & FITNESS -- Diseases -- General; MEDICAL -- Clinical Medicine; MEDICAL -- Diseases; MEDICAL -- Evidence-Based Medicine; MEDICAL -- Internal Medicine; Diabetes; Kidneys -- Diseases; Medicine; Nephrology; Kidney Diseases; Electronic books
• Languages: English
• ISBNs: 9783319234588; 3319234587; 3319234579; 9783319234571
• Related ISBNs: 9783319234571
• Notes: Note: Includes bibliographical references and index.; Note: Online resource; title from PDF title page (EBSCO, viewed January 19, 2016).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.