Kinesins and cancer. (2015)

• Record Type: Book
• Further Information: Note: Edited by Frank Kozielski.
• Editors: Kozielski, Frank
• Contents: Preface 1 The kinesin superfamily Kristen J. Verhey, Jared C. Cochran and Claire E. Walczak 2 The discovery and development of Eg5 inhibitors for the clinic James A.D. Good, G. Berretta, Nahoum G. Anthony and Simon P.Mackay 3 Mechanism of action of Eg5 inhibitors Robert A.Cross 4 Clinical trials of mitotic kinesin inhibitors Steven S.Rosenfeld 5 Kif15; a useful target for anti-cancer therapy? Roy G.H.P. van Heesbeen and Rene H.Medema 6 Down-regulating CENP-E activity: for better or for worse Julien Espeut and ArianeAbrieu 7 The human kinesin-14 motor KifC1/HSET is an attractive anti-cancer drug target Vaishali Pannu, Padmashree C.G. Rida and Ritu Aneja 8 Kinesin-13 Microtubule Depolymerizing Proteins as targets for cancer therapy Anutosh Ganguly and Fernando Cabral 9 Chromokinesins in genome maintenance and cancer Manjari Mazumdar and Tom Misteli 10 Kif14: a clinically relevent kineisn and potential target for cancer therapy Brigitte L. Theriault and Timothy W. Corson 11 Kinesin-8 members and their potnetial as biomarker or therapeutic target Thomas U. Mayer and Silke Hauf 12 The kinesin-6 members MKLP1, MKLP2 and MPP1 Ryan D. Baron and Francis Barr 13 Non-motor spindle proteins as cancer chemotherapy targets Bob Margolis and Mythili Yenjerla 14 Inhibitors of mitotic kinesins for cancer treatment: consequences for neurons Olga I. Kahn and Peter Baas Index .
• Publisher Details: Dordrecht : Springer
• Publication Date: 2015
• Copyright Date: 2015
• Extent: 1 online resource (271 pages)
• Subjects: 572.69; Kinesin -- Therapeutic use; Cancer -- Treatment
• Languages: English
• ISBNs: 9789401797320
• Related ISBNs: 9789401797313
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.