Transglutaminases : multiple functional modifiers and targets for new drug discovery /: multiple functional modifiers and targets for new drug discovery. (2015)

• Record Type: Book
• Further Information: Note: Kiyotaka Hitomi, Soici Kojima, Laszlo Fesus, editors.
• Editors: Hitomi, Kiyotaka; Kojima, Soichi; Fésüs, László
• Contents: 1 Structure of Transglutaminases. Unique Features Serve Diverse Functions -- 2 Control of Tg Functions Depending on their Localization -- 3 Preferred Substrate Structure of Transglutaminases -- 4 Insights into Transglutaminase 2 Function Gained from Genetically-Modified Animal Models -- 5 Tranglutaminase in Invertebrates -- 6 Formation of Integrin-Binding Site on Polymer of Transglutamination -- 7 Transglutaminase 2-Mediated Gene Regulation -- 8 The Role of Transglutaminase Type 2 in the Regulation of Autophagy -- 9 Transglutaminase 2 and Celiac Disease -- 10 Transglutaminase ii and Metastasis: How Hot is the Link?- 11 Transglutaminases: Expression in Kidney and Relation to Kidney Fibrosis -- 12 Transglutaminases in Bone Formation and Bone Matrix Stabilization -- 13 Transglutaminases and Neurological Diseases -- 14 Transglutaminase; Mechanism by Oxidative Stress -- 15 Blood Coagulation Factor Xiii : A Multifunctional Transglutaminase -- 16 Inhibition of Transglutaminase -- 17 Substrate Engineering of Microbial Transglutaminase for Site-Specific Protein Modification and Bioconjugation.
• Publisher Details: Tokyo : Springer
• Publication Date: 2015
• Extent: 1 online resource
• Subjects: 572/.792; 616.99/4; Transglutaminases; HEALTH & FITNESS -- Diseases -- General; MEDICAL -- Clinical Medicine; MEDICAL -- Diseases; MEDICAL -- Evidence-Based Medicine; MEDICAL -- Internal Medicine; Transglutaminases; Pharmacy, Therapeutics, & Pharmacology; Health & Biological Sciences; Biomedicine; Pharmaceutical Sciences/Technology; Animal Biochemistry; Enzymology; Electronic books
• Languages: English
• ISBNs: 9784431558255; 4431558233; 9784431558231
• Related ISBNs: 443155825X; 9784431558231
• Notes: Note: Includes bibliographical references and index.; Note: Online resource; title from PDF title page (EBSCO, viewed February 9, 2016).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.