Neurobiological and psychological aspects of brain recovery. ([2017])

• Record Type: Book
• Further Information: Note: Laura Petrosini, editor.
• Editors: Petrosini, Laura
• Contents: Preface; Contents; Contributors; 1 Structural Plasticity in Dendrites: Developmental Neurogenetics, Morphological Reconstructions, and Computational Modeling; Abstract; 1.1 Introduction; 1.2 Biomedical Relevance; 1.3 Developmental Neurogenetics; 1.3.1 Transcriptional Control of Dendritic Development and Cytoskeletal Modulation; 1.4 Neurogenetic and Neurogenomic Techniques; 1.5 Dendritic Reconstructions: Data Acquisition, File Formats, and Morphological Databases; 1.5.1 History and Progress in Tissue Labeling; 1.5.2 Advancements in Microscopy; 1.5.3 Advancements in Reconstruction Systems. 1.5.4 Large-Scale Databases1.5.5 File Formats and SWC; 1.6 Computational Modeling of Dendritic Growth; 1.7 Future Directions; Acknowledgements; References; 2 Autophagy Mechanisms for Brain Recovery. Keep It Clean, Keep It Alive; Abstract; 2.1 Introduction; 2.2 The Autophagy Machinery; 2.3 Basal Autophagy in Neurons; 2.4 The Role of Autophagy in Neurodevelopment and Neurogenesis; 2.5 Autophagy and Neurological Pathologies; 2.6 Autophagy in Neurodegenerative Diseases; 2.6.1 Alzheimer's Disease; 2.6.2 Parkinson's Disease; 2.6.3 Huntington's Disease; 2.7 Autophagy in CNS Trauma. 2.8 Traumatic Brain Injury2.9 Spinal Cord Injury; 2.10 Remote Degeneration After Focal CNS Damage; 2.11 Conclusions; Acknowledgements; 3 Environmental Enrichment Repairs Structural and Functional Plasticity in the Hippocampus; Abstract; 3.1 Effects of Experience in the Developing Brain; 3.2 Environmental Enrichment as Testable Scientific Concept; 3.3 Structural Changes; 3.3.1 Neurogenesis; 3.3.2 Postsynaptic Changes; 3.3.3 Presynaptic Changes; 3.3.4 Gliogenesis; 3.4 Functional Changes; 3.5 Hippocampus, EE and Disease; 3.5.1 Ischemia/Stroke; 3.5.2 Movement Disorders. 3.5.3 Inflammation and Stress3.5.4 Autism Spectrum Disorders; 3.6 Reopening of Critical Periods by EE: Therapeutic Implications; Acknowledgements; References; 4 Translatable Models of Brain and Cognitive Reserve; Abstract; 4.1 The Theory of Brain and Cognitive Reserve and Supporting Evidence in Humans; 4.2 Necessity and Design of Animal Models; 4.3 Experimental Paradigms to Study BCR; 4.3.1 Animal Models of Brain Ageing; 4.3.2 Environmental Enrichment (EE); 4.3.3 Voluntary Exercise; 4.3.4 Antioxidants; 4.4 Putative Neurobiological Mechanisms of BCR; 4.4.1 Overview. 4.4.2 Synaptic, Cellular and Physiological Mediators4.4.2.1 Synaptogenesis and Synaptic Plasticity; 4.4.2.2 Adult Hippocampal Neurogenesis; 4.4.2.3 Glial Contributions; 4.4.2.4 Vascular Alterations; 4.4.3 Molecular Regulators; 4.4.3.1 Gene Expression, Epigenetic and Chromatin Modifications; 4.4.3.2 Neurotrophins; 4.4.3.3 Neurotransmitter and Neuromodulator Dynamics; 4.5 Conclusion; 4.5.1 Enviromimetics; 4.5.2 Room for Improvement; 4.5.3 Summary; References; 5 Cognitive Reserve: A Life-Course Perspective; Abstract; 5.1 Introduction; 5.2 Early Adulthood: Educational Attainment.
• Publisher Details: Cham, Switzerland : Springer
• Publication Date: 2017
• Copyright Date: 2017
• Extent: 1 online resource
• Subjects: 617.4810443; Brain -- Wounds and injuries -- Patients -- Rehabilitation; Brain damage -- Psychological aspects; Developmental neurobiology; MEDICAL -- Neurology; Brain damage -- Psychological aspects; Brain -- Wounds and injuries -- Patients -- Rehabilitation; Developmental neurobiology; Biomedicine; Neurosciences; Neuropsychology; Neurology; Brain injuries -- therapy; Neurological Rehabilitation; Recovery of Function; Electronic books
• Languages: English
• ISBNs: 9783319520674; 3319520679
• Related ISBNs: 9783319520650; 3319520652
• Notes: Note: Includes bibliographical references and index.; Note: Online resource, title from PDF title page (EBSCO, viewed March 17, 2017).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.