Cell-based therapy for degenerative retinal disease. (2019)

• Record Type: Book
• Further Information: Note: Marco A. Zarbin, Mandeep S. Singh, Ricardo P. Casaroli-Marano, editors.
• Editors: Zarbin, Marco A; MD, Singh, Mandeep; Casaroli-Marano, Ricardo Pedro
• Contents: Intro; Preface; Contents; Contributors; Chapter 1: Advantages of the Eye as a Target Organ for Cell-Based Therapy in the Central Nervous System; Introduction; Advantages of the Eye as a Target Organ; Anatomy and Physiology; Surgical Access; Immune Privilege; Antigen Load; High-Resolution Noninvasive Imaging Technology; Functional Assessment of the Transplant; Conclusions; References; Chapter 2: Proof of Principle: Preclinical Data on Retinal Cell Transplantation; Introduction; Photoreceptor Rescue Therapy; RPE Transplantation; Neural and Retinal Progenitor Cell Transplantation Bone Marrow Cell TransplantationUmbilical Tissue-Derived Cell Transplantation; Photoreceptor Replacement Therapy; Neuroretinal Sheet Transplantation; Photoreceptor Cell Transplantation; Retinal Cellular Materials Transfer; Conclusion; References; Chapter 3: Clinical and Pathological Features of Selected Human Retinal Degenerative Diseases; Introduction; Generalized Retinal Degenerations; Retinitis Pigmentosa; Clinical Characteristics; Genetic Associations and Pathophysiology; Ophthalmoscopic Features; Imaging and Other Useful Tests; Perimetry and Electrophysiological Testing Fundus AutofluorescenceFluorescein Angiography; Optical Coherence Tomography (OCT); Differential Diagnosis; Leber Congenital Amaurosis; Clinical Characteristics; Genetic Association and Pathophysiology; Ophthalmoscopic Features; Imaging and Other Useful Tests; Fundus Autofluorescence, Fluorescein Angiography, and OCT; Psychophysical and Electrophysiological Testing; Differential Diagnosis; Choroideremia; Clinical Characteristics; Genetic Association and Pathophysiology; Ophthalmoscopic Features; Imaging and Other Useful Tests; Differential Diagnosis; Central Degenerations Age-Related Macular DegenerationClinical Characteristics; Genetic Association and Pathophysiology; Ophthalmoscopic Features; Imaging and Other Useful Tests; Fluorescein Angiography; Optical Coherence Tomography; Fundus Autofluorescence; Electrophysiological Testing; Differential Diagnosis; ABCA4 (Stargardt) Dystrophy; Clinical Characteristics; Genetic Association and Pathophysiology; Ophthalmoscopic Features; Imaging and Other Useful Tests; Fundus Autofluorescence; Fluorescein Angiography; Optical Coherence Tomography; Electrophysiological Testing; Differential Diagnosis; Best Disease Clinical CharacteristicsGenetic Association and Pathophysiology; Ophthalmoscopic Features; Imaging and Other Useful Tests; Optical Coherence Tomography; Fundus autofluorescence; Fluorescein Angiography; Electrophysiological Testing; Differential Diagnosis; Conclusion; References; Chapter 4: Degenerative Retinal Diseases: Cell Sources for Cell-Based Therapy; Retinal Degenerative Diseases; Sources of Stem Cells; Embryonic Stem Cells (ESCs); Fetal Stem Cells; Adult Stem Cells; Neuronal Origin; RPE Stem Cells; Ciliary Epithelium-Derived Progenitor Cells; Müller Progenitor Cells (MCs)
• Publisher Details: Cham, Switzerland : Humana Press
• Publication Date: 2019
• Extent: 1 online resource (xi, 280 pages), illustrations (some color)
• Subjects: 617.7/35; Retinal degeneration -- Treatment; Stem cells -- Therapeutic use; Electronic books; Electronic books
• Languages: English
• ISBNs: 9783030052225; 3030052222
• Related ISBNs: 9783030052218
• Notes: Note: Online resource; title from PDF title page (SpringerLink, viewed March 6, 2019).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.