Adeno-Associated Virus Vectors : Design and Delivery /: Design and Delivery. (2019)

• Record Type: Book
• Further Information: Note: Michael J. Castle.
• Editors: Castle, Michael J
• Contents: Part I: Gene Delivery to the Central Nervous System Chapter 1. Stereotactic Intraparenchymal Injection for Gene Delivery to the Brain Chapter 2. MRI-Guided Intraparenchymal Injection for Gene Delivery to the Brain (Krystof Bankiewicz) Chapter 3: Intravenous Infusion for Widespread Delivery to Nervous and Peripheral Tissues (Brian Kaspar) Chapter 4: MRI-Guided Focused Ultrasound for Targeted Gene Delivery to the Brain (Isabelle Aubert) Chapter 5: Intrathecal Infusion for Gene Delivery to the Nervous System (Mark Tuszynski and myself) Chapter 6: Direct Intraparenchymal Injection for Gene Delivery to the Spinal Cord Chapter 7: Retrograde Targeting of Spinal Motor Neurons by Muscle Injection Chapter 8: Subpial Infusion for Widespread Gene Delivery to the Spinal Cord Chapter 9: Intraganglionic Microinjection for Gene Delivery to the DRG Chapter 10: Intravitreal Injection for Gene Delivery to the Eye Chapter 11: Subretinal Injection for Gene Delivery to the Eye (Luk Vandenberghe) [Chapters 10 and 11 could be combined into a single chapter for ocular delivery] Part II: Gene Delivery to Peripheral Tissues Chapter 12: Intranasal Administration for Gene Delivery to the Lung Chapter 13: Orotracheal Administration for Gene Delivery to the Lung Chapter 14: Surgical Tracheal Administration for Gene Delivery to the Lung [Chapters 13 and 14 could be combined into a single chapter for tracheal delivery] Chapter 15: Infusion of Coronary Artery for Global Gene Delivery to the Heart Chapter 16: Aortic Occlusion and Pressurized Infusion for Global Gene Delivery to the Heart [Chapters 15 and 16 could be combined into a single chapter for global heart delivery] Chapter 17: Intramyocardial Injection for Targeted Gene Delivery to the Heart Chapter 18: Intraportal Vein Injection for Global Gene Delivery to the Liver Chapter 19: Intraparenchymal Injection for Targeted Gene Delivery to the Liver Chapter 20: Gene Delivery to the Spleen Chapter 21: Gene Delivery to the Kidney Chapter 22: Gene Delivery to Skeletal Muscle Part III: Design of Novel Vectors for Targeting of Specific Tissues and Cell Types Chapter 23: Design of AAV vectors for Delivery of Large or Multiple Transgenes Chapter 24: Design of AAV vectors for Delivery of RNAi Chapter 25: Altering AAV tropism with Directed Evolution Chapter 26: Altering AAV tropism with AAV-CREATE (Ben Deverman) Chapter 27: Altering AAV tropism with Phage Display (Tomas Bjorklund) Chapter 28: Minipromoters for Tissue- and Cell-Specific Gene Expression (Elizabeth Simpson).
• Publisher Details: New York : Humana Press
• Publication Date: 2019
• Copyright Date: 2019
• Extent: 1 online resource (426 pages)
• Subjects: Medicine; Medical -- Microbiology; Medical microbiology & virology; Human genetics; Medical virology; Medical -- Genetics; Medical genetics
• Languages: English
• ISBNs: 9781493991396
• Related ISBNs: 9781493991389
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.