Advances in nucleic acid therapeutics. (2019)

• Record Type: Book
• Further Information: Note: Edited by Sudhir Agrawal, Michael J. Gait.
• Editors: Agrawal, Sudhir; Gait, M. J (Michael J.)
• Contents: History and Development of Nucleotide Analogues in Nucleic Acids Drugs; Mechanisms of Antisense Oligonucleotides; The Medicinal Chemistry of RNase H-activating Antisense Oligonucleotides; Antisense Technology: Liver Targeting and Beyond for Drug Discovery; Oligonucleotide-based Toll-like Receptor Antagonists and Therapeutic Applications; Splicing Modulation for Therapeutics; Targeting Toxic Repeats; Research and Development of Oligonucleotides Targeting MicroRNAs (miRNAs); Oligonucleotide Targeting of Long Non-coding RNAs; Conjugate-mediated Delivery of RNAi-based Therapeutics: Enhancing Pharmacokinetics-Pharmacodynamics Relationships of Medicinal Oligonucleotides; Liver-targeted RNAi Therapeutics: Principles and Applications; Advances and Challenges of RNAi-Based Anti-HIV Therapeutics; Nucleic Acid Innate Immune Receptors; Synthetic Agonists of Toll-like Receptors and Therapeutic Applications; Prostate-specific Membrane Antigen (PSMA) Aptamers for Prostate Cancer Imaging and Therapy; Aptamers and Clinical Applications; CRISPR-based Technologies for Genome Engineering: Properties, Current Improvements and Applications in Medicine; Therapeutic Potential of Ribozymes; Large-scale Automated Synthesis of Therapeutic Oligonucleotides: A Status Update; Preclinical and Clinical Drug-metabolism, Pharmacokinetics and Safety of Therapeutic Oligonucleotides; Subject Index
• Edition: 1st
• Publisher Details: Cambridge : Royal Society of Chemistry
• Publication Date: 2019
• Extent: 1 online resource
• Subjects: 615.31; Nucleic acids -- Therapeutic use
• Languages: English
• ISBNs: 9781788017329; 9781788015714
• Related ISBNs: 9781788012096
• Notes: Note: Description based on CIP data; resource not viewed.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.