Therapeutic Application of Nitric Oxide in Cancer and Inflammatory Disorders. ([2019])

• Record Type: Book
• Further Information: Note: Lucia Morbidelli, Benjamin Bonavida.
• Authors: Morbidelli, Lucia; Bonavida, Benjamin
• Contents: I. Applications of Nitric Oxide in Cancer 1. Nitric Oxide-Releasing Engineered Nanoparticles: Tools for Overcoming Drug Resistance in Chemotherapy 2. Reversal of Multiple Cancer Oncogenic Pleiotropic Properties by NO-modulating Therapies 3. Antitumor Effect of a Metal Nonoate Through Angiogenesis Impairment 4. Therapeutic Implications of the Nitric Oxide Pathway in the Angiogenesis of Tumors and Inflammatory-Related Disorders 5. Nitric oxide and cancer: To inhibit or to induce iNOS – That is the Question? 6. Arginine Metabolism Regulates Nitric Oxide Production in Melanoma Tumor Microenvironment to Provide Survival Advantage to Tumor Cells 7. Cancer and Beyond: Discovery and Development of NO-releasing Therapeutics 8. Nitric Oxide Scavenging-Based Therapies for Targeting Colorectal Cancer 9. Therapeutic Aspects of Protein Denitrosylation 10. Nitric Oxide-Releasing Functional Nanomaterials for Anticancer Therapy II. Applications of Nitric Oxide in Inflammatory-Related Disorders 11. The Role of Nitric Oxide on Vascular Dysfunction During Aging and Alzheimer’s Disease 12. Carbonic Anhydrase Inhibitor – NO Donor Hybrids and Their Pharmacologic Applications 13. Understanding the Roles of Nitric Oxide During Sepsis, an Inflammatory Disorder 14. Nanoporous Materials: New Generation of Nitric Oxide Donors III. Abstracts (Presentations at Conference in Siena, October 4th-5th, 2018) A. Serum Nitric Oxide Metabolites and The Incidence of Metabolic Syndrome and Its Phenotypes: A Population-Based Prospective Study B. Nitric Oxide (NO): A Multifaceted Target for Reversal of Cancer Cell Pleiotropic Properties by NO-modulating Therapies C. Pharmacology of Hepatoselective Nitric Oxide - Donors in NAFLD in Mice D. New NO-Releasing Doxorubicins as Targeted Therapy Against Chemoresistance in Castration-resistant Prostate Cancer: In Vitro and In Vivo Evaluations E. Anticancer Effect of a Novel H2S-Hybrid Molecule on Human Breast Adenocarcinoma (MFC-7) and Human Breast Epithelial (MCF-10A) Cell Lines F. Heme Oxygenase-1 In Duchenne Muscular Dystrophy: Interaction with Nitric Oxide Synthase Pathway in Satellite Cells Differentiation G. In Vitro Assessment of NitDox Toxicity Towards Vasculature H. The Regulation of GSNOR Expression Discloses the Role of S-nitrosylation in Aging and Disease I. Effects of Long-term Nitrite Supplementation on Gene Expressions of GLUT2, GLUT4 and Glucokinase in Male Obese Type 2 Diabetic Rats J. Nitric Oxide Re-Instates Doxorubicin Cytotoxic and Pro-Immunogenic Effects in Refractory Breast Cancer K. Anti-Cancer Activities of Erucin a H2S-donor Isothiocyanate from Eruca Sativa Mill.: Is H2S the Real Player? L. Hydrogen Sulfide as a Signaling Molecule in The Cardiovascular System: Actions and Interactions with NO M. Nitric Oxide in Cancer Resistance to Cisplatin: Tumor Associated Macrophages as Key Players. N. Therapeutic Potential of Nitric Oxide Modulation in Ocular Diseases: A Focus on Novel NO-Releasing Molecules O. Pro-Apoptotic Effects of S-Nitrosothiols O-Chloro and M-Chloro S-Nitroso-Aryl-Amides in Human Breast Cancer Cell Lines P. Light Guided Production of Nitric Oxide and Singlet Oxygen for the Multi-Modal Treatment of Cancer Q. Potential for Chemoprevention with Nitric Oxide- and Hydrogen Sulfide-Releasing Drugs R. H2S Metabolism in Colon Cancer Cells Exposed to Hypoxia
• Publisher Details: London, United Kingdom : Academic Press, an imprint of Elsevier
• Publication Date: 2019
• Copyright Date: 2019
• Extent: 1 online resource
• Subjects: 612/.01524; Nitric oxide -- Physiological effect; Nitric oxide -- Pathophysiology; Nitric oxide -- Therapeutic use; Cancer -- Treatment; Inflammation -- Treatment; MEDICAL / Physiology; SCIENCE / Life Sciences / Human Anatomy & Physiology; Electronic books
• Languages: English
• ISBNs: 9780128172797; 0128172797; 9780128165454; 0128165456
• Notes: Note: Includes bibliographical references and index.; Note: Online resource; title from PDF title page (EBSCO, viewed February 13, 2019).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.