Biochemical roles of eukaryotic cell surface macromolecules. (2015)

• Record Type: Book
• Further Information: Note: Abhijit Chakrabarti.
• Authors: Chakrabarti, Abhijit
• Contents: Preface; Contents; Chapter 1: Human-Specific Evolutionary Changes in the Biology of Siglecs; Introduction; Human-Specific Changes in Siglecs; Siglec-1/Sialoadhesin; Siglec-3/CD33; Siglec-5 and -14; Siglec-6; Siglec-9; Siglec-11 and -16; Siglec-XII; Siglec-13; Siglec-17; Conclusions and Perspectives; References; Chapter 2: Structural Changes of GPI Anchor After Its Attachment to Proteins: Functional Significance; Introduction; Biosynthesis of GPI and Its Attachment to Proteins; GPI Remodeling Reactions That Occur After Attachment to Proteins; Inositol-Deacylation by PGAP1 in the ER. Removal of an EtNP Side Branch from the Second Mannose by PGAP5 in the ER Fatty Acid Remodeling of GPI-AP in the Golgi; Biological Significance of Fatty Acid Remodeling; References; Chapter 3: Novel Insights in Membrane Biology Utilizing Fluorescence Recovery After Photobleaching; The Dynamic Membrane; Fluorescence Recovery After Photobleaching; Lipid Dynamics by FRAP; GPCR Activation: Manifestations in Receptor Dynamics; Dynamic Confinement of GPCRs Upon Cholesterol Depletion: Insight from Bleach Area-Dependent FRAP; Are Signaling and Dynamics Correlated? Lateral Dynamics as Readout of Infection Conclusion and Future Perspectives; References; Chapter 4: Defects in Erythrocyte Membrane Skeletal Architecture; Introduction; Membrane Skeleton; Erythroid Membrane Skeleton; Lipid Bilayer: Membrane Skeleton Interactions; Assembly of the Membrane-Skeleton of Erythroid Cells; Defects in Membrane Skeleton; Hereditary Spherocytosis; Molecular Defects in HS; Pathophysiology; Laboratory Features and Treatment; Hereditary Elliptocytosis; Molecular Defects in HE; Laboratory Features and Treatment; Malaria and the Erythrocyte Membrane Skeleton Alterations. ConclusionReferences; Chapter 5: Membrane Rafts in the Erythrocyte Membrane: A Novel Role of MPP1p55; Introduction; Erythrocyte Membrane Rafts; Stomatin, Flotillins and MPP1 Are the Stable Components of Erythrocyte Rafts; Stomatin; Flotillins; MPP1; Visualization of Erythrocyte Membrane Rafts; Role of Erythrocyte Membrane Rafts in Signaling; Erythrocyte Rafts and Pathology; MPP1 and Its Palmitoylation Play a Crucial Role in Lateral Membrane Organization in Erythroid Cells; The Involvement of Actin in Erythrocyte Membrane Rafts Organization?; Conclusions; References.
• Publisher Details: Cham, Switzerland : Springer
• Publication Date: 2015
• Copyright Date: 2015
• Extent: 1 online resource (407 pages), illustrations (some color), tables
• Subjects: 574.87; Eukaryotic cells; Molecular biology; Cell receptors; Cell receptors; Eukaryotic cells; Molecular biology; Chemistry; Carbohydrate Chemistry; Membrane Biology; Electronic books
• Languages: English
• ISBNs: 9783319112800; 3319112805
• Related ISBNs: 9783319112794; 3319112791; 9783319112794
• Notes: Note: Includes bibliographical references and index.; Note: Print version record.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.