Validation of alternative methods for toxicity testing. ([2016])

• Record Type: Book
• Further Information: Note: Chantra Eskes, Maurice Whelan, editors.
• Editors: Eskes, Chantra; Whelan, Maurice
• Contents: Introduction / Chantra Eskes, Maurice Whelan -- Validation in support of internationally harmonised OECD test guidelines for assessing the safety of chemicals / Anne Gourmelon, Nathalie Delrue -- Regulatory acceptance of alternative methods in the development and approval of pharmaceuticals / Sonja Beken, Peter Kasper, Jan-Willem van der Laan -- Validation of alternative in vitro methods to animal testing: concepts, challenges, processes and tools / Claudius Griesinger, Bertrand Desprez, Sandra Coecke, Warren Casey, Valérie Zuang -- Practical aspects of designing and conducting validation studies involving multi-study trials / Sandra Coecke [and others] -- Validation of computational methods / Grace Patlewicz, Andrew P. Worth, Nicholas Ball -- Implementation of new test methods into practical testing / Rodger D. Curren, Albrecht Poth, Hans A. Raabe -- Pathway based toxicology and fit-for-purpose assays / Rebecca A. Clewell [and others] -- Evidence-based toxicology / Sebastian Hoffmann, Thomas Hartung, Martin Stephens -- Validation of transcriptomics-based in vitro methods / Raffaella Corvi, Mireia Vilardell, Jiri Aubrecht, Aldert Piersma -- Ensuring the quality of stem cell-derived in vitro models for toxicity testing -- Glyn N. Stacey, Sandra Coecke, Anna-Bal Price, Lyn Healy, Paul Jennings, Anja Wilmes & -- Validation of bioreactor and human-on-a-chip devices for chemical safety assessment -- Sofia P. Rebelo [and others] -- Integrated approaches to testing and assessment / Andrew P. Worth, Grace Patlewicz -- International harmonization and cooperation in the validation of alternative methods / João Barroso [and others] -- Evolving the principles and practice of validation for new alternative approaches to toxicity testing / Maurice Whelan, Chantra Eskes.
• Publisher Details: [Cham] Switzerland : Springer
• Publication Date: 2016
• Copyright Date: 2016
• Extent: 1 online resource (xx, 407 pages), illustrations (some color)
• Subjects: 615.9/07; 610; Alternative toxicity testing -- Methodology; MEDICAL -- Pharmacology; Biomedicine; Pharmaceutical Sciences/Technology; Molecular Medicine; Medicine; Molecular biology; Pharmaceutical technology; Animal Testing Alternatives -- methods; Animal Testing Alternatives -- standards; Benchmarking; In Vitro Techniques; Models, Biological; Toxicity Tests -- methods; Toxicity Tests -- standards; Electronic books
• Languages: English
• ISBNs: 9783319338262; 3319338269
• Related ISBNs: 9783319338248; 3319338242
• Notes: Note: Includes bibliographical references and index.; Note: Online resource; title from pdf title page (SpringerLink, viewed October 4, 2016).; Note: Print version record.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.