Targeted therapy of colorectal cancer subtypes. (2018)

• Record Type: Book
• Further Information: Note: Peter Jordan, editor.
• Editors: Jordan, Peter
• Contents: Preface Chapter 1- Colorectal Cancer Subtypes- the current portrait. 1 Peter Jordan Chapter 2- Targeting colon cancers with mutated BRAF and microsatellite instability. 17 Paulo Matos and Peter Jordan Chapter 3 - Targeting KRAS mutant CMS3 subtype by metabolic inhibitors. 50 Oscar Aguilera and Roberto Serna-Blasco Chapter 4- Targeting the PI3K Signalling as a Therapeutic Strategy in Colorectal Cancer. 77 Maria Sofia Fernandes, João Miguel Sanches and Raquel Seruca Chapter 5- Targeting PTEN in colorectal cancers. 117 Larissa Kotelevets, Mark G.H. Scott and Eric Chastre Chapter 6- Wnt signalling-targeted therapy in the CMS2 tumour subtype: a new paradigm in CRC treatment? 162 Cristina Albuquerque and Lucília Pebre Pereira Chapter 7- Impact of the microenvironment on tumour budding in colorectal cancer. 216 Laurent MC Georges, Laurine Verset, Inti Zlobec, Pieter Demetter, Olivier De Wever Chapter 8- Anti-EGFR Therapy to treat metastatic colorectal cancer: not for all 241 Marta Martins, André Mansinho, Raquel Duarte, Soraia Lobo Martins and Luís Costa Chapter 9- miRNAs as modulators of EGFR therapy in colorectal cancer. 282 Diane M. Pereira and Cecília M. P. Rodrigues Index.
• Publisher Details: Cham, Switzerland : Springer
• Publication Date: 2018
• Extent: 1 online resource (viii, 150 pages), color illustrations
• Subjects: 616.99/4347061; Colon (Anatomy) -- Cancer -- Chemotherapy; Rectum -- Cancer -- Chemotherapy; Drug targeting; Electronic books
• Languages: English
• ISBNs: 9783030027711; 3030027716
• Related ISBNs: 9783030027704
• Notes: Note: Online resource; title from PDF title page (SpringerLink, viewed January 23, 2019).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.