T-cell and NK-cell lymphomas : from biology to novel therapies /: from biology to novel therapies. ([2019])

• Record Type: Book
• Further Information: Note: Editors, Christiane Querfeld, Jasmine Zain and Steven T. Rosen.
• Editors: Querfeld, Christiane; Zain, Jasmine; Rosen, Steven T
• Contents: Intro; Contents; About the Editors; 1 Epidemiology and Pathology of T- and NK-Cell Lymphomas; Abstract; 1.1 Introduction; 1.2 Epidemiology; 1.3 Nodal Peripheral T-Cell Lymphomas; 1.3.1 Angioimmunoblastic T-Cell Lymphoma and Other Nodal Lymphomas TFH-Cell Origin; 1.3.2 Peripheral T-Cell Lymphoma, NOS; 1.3.3 Anaplastic Large-Cell Lymphomas; 1.3.4 Intestinal T-Cell Lymphomas; 1.3.5 Enteropathy-Associated T-Cell Lymphoma (EATL); 1.3.6 Monomorphic Epitheliotropic Intestinal T-Cell Lymphoma (MEITL); 1.3.7 Intestinal T-Cell Lymphoma, NOS 1.3.8 Indolent T-Cell Lymphoproliferative Disorder of the Gastrointestinal Tract1.3.9 Hepatosplenic T-Cell Lymphoma; 1.4 Cutaneous T-Cell Lymphoproliferative Disorders; 1.4.1 Subcutaneous Panniculitis-like T-Cell Lymphoma (SPTCL); 1.4.2 Primary Cutaneous Gamma-Delta T-Cell Lymphoma (PCGD-TCL); 1.4.3 Mycosis Fungoides; 1.4.4 Sézary Syndrome; 1.5 Adult T-Cell Leukemia/Lymphoma; 1.6 Extranodal NK/T-Cell Lymphoma, Nasal Type (ENKTCL); 1.7 Conclusion; References; 2 Molecular and Genomic Landscape of Peripheral T-Cell Lymphoma; Abstract; 2.1 Introduction 2.2 T-Cell Development and Activation: An Overview2.3 TCR Rearrangement in the Diagnosis of PTCL; 2.4 Pathobiology of PTCL with Molecular Genomic Approaches; 2.5 Peripheral T-Cell Lymphoma, Not Otherwise Specified (PTCL-NOS); 2.6 Gene Expression Profiling Revealed Biological Subgroups in PTCL-NOS; 2.7 Genetic Studies Demonstrated Distinct Entities Within PTCL-NOS; 2.8 Limited MicroRNA Profiling Studies in PTCL-NOS; 2.9 Angioimmunoblastic T-Cell Lymphoma (AITL); 2.10 Anaplastic Large Cell Lymphoma (ALCL); 2.11 Adult T-Cell Leukemia/Lymphoma (ATLL); 2.12 Cutaneous T-Cell Lymphoma (CTCL) 2.13 ENK/T-Cell Lymphomas2.14 The Expanding Scope of Genomics for Therapeutic Opportunities in PTCLs; References; 3 Tumor Microenvironment in T-Cell Lymphomas; Abstract; 3.1 Introduction; 3.2 Components of the Tumor Microenvironment in T-Cell Lymphomas; 3.2.1 Tumor-Infiltrating Lymphocytes; 3.2.2 Intratumoral Macrophages; 3.3 Clinical Implications; 3.3.1 Therapeutic Targets; References; 4 Peripheral T-Cell Lymphoma, not Otherwise Specified (PTCL-NOS); Abstract; 4.1 Introduction; 4.2 Epidemiology and Risk Factors 4.3 Pathological Classification, Gene Expression Profiling, and Mutational Landscape4.4 Clinical Presentation and Staging; 4.5 Prognostic Factors and Risk Stratification; 4.6 Treatment Strategies; 4.6.1 Front Line; 4.6.2 High-Dose Chemotherapy (HDCT) and Autologous Hematopoietic Stem Cell Transplantation (ASCT); 4.7 Allogeneic Stem Cell Transplantation; 4.8 Treatment of Relapsed or Refractory Patients; 4.8.1 Therapy in Transplant Ineligible Patients; 4.8.2 Limited Stage and Role of Radiation; 4.8.3 CNS Involvement and Prophylaxis; References; 5 Angioimmunoblastic T-Cell Lymphoma; Abstract
• Publisher Details: Cham, Switzerland : Springer
• Publication Date: 2019
• Extent: 1 online resource
• Subjects: 616.99446; Lymphomas; T cells; Killer cells; HEALTH & FITNESS / Diseases / General; MEDICAL / Clinical Medicine; MEDICAL / Diseases; MEDICAL / Evidence-Based Medicine; MEDICAL / Internal Medicine; Electronic books
• Languages: English
• ISBNs: 9783319997162; 3319997165
• Related ISBNs: 9783319997155; 3319997157
• Notes: Note: Includes bibliographical references.; Note: Online resource; title from PDF title page (EBSCO, January 3, 2019).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.