Lessons on caffeine, cannabis & Co : plant-derived drugs and their interaction with human receptors /: plant-derived drugs and their interaction with human receptors. (2018)

• Record Type: Book
• Further Information: Note: Angelika Böttger, Ute Vothknecht, Cordelia Bolle, Alexander Wolf.
• Authors: Böttger, Angelika; Vothknecht, Ute; Bolle, Cordelia; Wolf, Alexander
• Contents: Introduction: Plant secondary metabolites and their general function in plants.- Historical and current perspective.- Medicinal use.- Recreational use.- General overview over biosynthesis pathways of plant secondary metabolites.- Drugs affecting GPCR: GPCRs in plants and animals.- Dopamine and 5-HT2A-serotonin receptors – Cocaine, mescaline, psilobin.- Opiate receptors – morphine, salvinorin A.- Cannabinoid receptors – THC.- Muscarinergic acetylcholin receptor - muscarin, atropine.- Adenosine receptor – caffeine.- Drugs affecting ion channels: Ligand and voltage activated channels.- Nicotinic acetylcholin receptor – Nicotine, Curare.- GABAA/C-receptor – Muscimol, thujone.- ionotropic Glycine receptor – Strychnine.- ionotropic Glutamate receptor - ibogtenic acid, kainic acid.- TRP channels – capsaicin, menthol, aconitine, resiniferatoxin.- Anti-cancer drugs acting on the cell cycle: Cell cycle in animals and plants.- Microtubuli - Colchicine, taxol, vinblastine, Podophyllotoxin (Lignan).- Topoisomerase - camptothecin, etoposide.- G2/M phase arrest, apoptosis – curcubitacin, triptolide.
• Publisher Details: Cham, Switzerland : Springer
• Publication Date: 2018
• Extent: 1 online resource (x, 217 pages), illustrations (some color)
• Subjects: 613.8/4; Caffeine -- Physiological effect; Cannabis -- Physiological effect; Electronic books
• Languages: English
• ISBNs: 9783319995465; 3319995464
• Related ISBNs: 9783319995458
• Notes: Note: Online resource; title from PDF title page (SpringerLink, viewed January 11, 2019).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.