Cadmium Interaction with Animal Cells. (2018)

• Record Type: Book
• Further Information: Note: Frank Thévenod, David Petering, Douglas M. Templeton, Wing-Kee Lee, Andrea Hartwig, editors.
• Other Names: Thévenod, F (Frank); Petering, David; Templeton, Douglas M; Lee, Wing-Kee; Hartwig, Andrea
• Contents: Intro; Preface; References; Contents; 1 Membrane Transport Proteins and Receptors for Cadmium and Cadmium Complexes; 1.1 Introduction; 1.2 Channels and Pores; 1.2.1 Ca2+ Channels; 1.2.2 Mitochondrial Calcium Uniporter (MCU); 1.2.3 Cystic Fibrosis Transmembrane Conductance Regulator (CFTR/ABCC7); 1.2.4 Gap Junction-Forming Connexins; 1.3 Solute Carriers (SLCs); 1.3.1 Divalent Metal Transporter 1 (DMT1/DCT1/NRAMP2/SLC11A2); 1.3.2 Zip8/Zip14 (SLC39A8/A14); 1.3.3 Organic Cation Transporter 2 (SLC22A2) and Multi-antimicrobial Extrusion (MATE) Proteins (SLC47A1/A2) 1.3.4 Amino Acid/Cystine Transporter (SLC7A9/SLC3A1)1.3.5 Ferroportin-1 (FPN1/SLC40A1); 1.4 ATPASES; 1.4.1 Multidrug Resistance P-Glycoprotein (MDR1/ABCB1); 1.4.2 Multidrug Resistance-Associated Protein 1 (MRP1/ABCC1); 1.5 Receptors; 1.5.1 Lipocalin-2 Receptor (Lip2-R/SLC22A17); 1.5.2 Megalin: Cubilin; 1.5.3 Transferrin Receptor 1 (TfR1); 1.6 Summary, Conclusions and Outlook; References; 2 The Chemical Biology of Cadmium; 2.1 Introduction; 2.2 Inorganic Biochemical Framework for Cd2+ Toxicology; 2.3 Metallothionein and the Proteome: Reactions with Cd2+ and Zn2+ 2.4 MTF-1: Reactions with Cd2+ and Zn2+2.5 Reactions of Cd2+ with Metallothionein in Relation to Animal Toxicity; 2.6 Reactions of Cd2+ with Zn-Proteins in Relation to Nephrotoxicity: Zn3-SP1; 2.7 Reactions of Cd2+ with Zn-Proteins in Relation to Carcinogenesis; 2.8 Reactions of Cd2+ Related to Apoptosis; 2.9 Reactions of Cd2+ with Zn-Proteins in Relation to Signal Transduction; 2.10 Interactions of Cd2+ with Iron, Copper, and Calcium; 2.11 Analytical Methodology to Detect Cd-Proteins; References; 3 Interactions of Cadmium with Signaling Molecules; 3.1 Introduction
• Publisher Details: Cham : Springer
• Publication Date: 2018
• Extent: 1 online resource
• Subjects: 571.9/54662; Cadmium -- Physiological effect; Cadmium -- Toxicology; Electronic books
• Languages: English
• ISBNs: 9783319896236; 3319896237
• Related ISBNs: 9783319896229; 3319896229
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.