Surface enhanced raman spectroscopy for biophysical applications : using plasmonic nanoparticle assemblies /: using plasmonic nanoparticle assemblies. (2018)

• Record Type: Book
• Further Information: Note: Claudia Fasolato.
• Authors: Fasolato, Claudia
• Contents: Intro; Supervisor's Foreword; Abstract; Parts of this thesis have been published in the following articles; Acknowledgements; Contents; 1 Introduction; References; 2 Traditional Raman and SERS: Fundamentals and State of the Art; 2.1 Optical Vibrational Spectroscopy of Molecules; 2.1.1 Theory of Raman Scattering; 2.2 Surface Enhanced Raman Scattering; 2.2.1 Electromagnetic Mechanism; 2.2.2 Chemical Mechanism; 2.3 Current Trends in Surface Enhanced Raman Scattering; 2.3.1 Nanoparticle-Based SERS Substrates; 2.3.2 SERS Applications in Nanomedicine 2.3.3 Non Metallic Substrates: SERS from Semiconductor NanostructuresReferences; 3 Investigation on Nanoparticles and Their Molecular Functionalization; 3.1 Model Functionalization with 4ATP Linker; 3.1.1 Preparation and Control Characterization; 3.1.2 SERS Versus Raman Spectrum; 3.2 Further Conjugation: Folate and Antifolates; 3.2.1 Nanovector Functionalization: The Case of Folate; 3.2.2 SERS Signature of Folate/Antifolate Nanovectors; 3.3 Experimental Details; References; 4 Nanoparticle-Based SERS Substrates for Molecular Sensing Applications 4.1 Self-assembled Mesoscopic Silver Nanoparticle Clusters4.1.1 Coupled AFM and Raman Analysis; 4.1.2 Dimensional Scale Effect on SERS Efficiency; 4.2 FDTD Simulation: Theoretical Predictions; 4.2.1 The FDTD Software; 4.2.2 Results on Silver and Gold Np Multilayers; 4.3 Electron Beam Lithography Driven Self-assembly; 4.3.1 Nanoparticle Cluster Array Preparation; 4.3.2 Analysis of the Patterned Arrays; 4.3.3 Analysis of the Ordered Nanoparticle Cluster Arrays; 4.3.4 SERS Reproducibility; References; 5 SERS-Active Nanovectors for Single-Cell Cancer Screening and Theranostics 5.1 Early Cancer Diagnostics and Theranostics5.2 Folate-Based SERS Diagnostics; 5.2.1 Idea of the Experiment; 5.2.2 Cell Treatment and Viability Tests; 5.2.3 Raman and SERS Imaging on Treated Cells; 5.2.4 SEM Imaging on Treated Cells; 5.2.5 SERS Screening and Results; 5.3 From Selectivity to Theranostics: Antifolate Nanovectors; 5.3.1 Preliminary Cytotoxicity Results; 5.3.2 Enhanced Toxicity of Nanostructured Drugs; References; 6 Conclusions; A SERS Application in Cultural Heritage; A.1 HPTLC-SERS Investigation of Madder Lake Ammonia Extract; A.1.1 HPTLC-SERS Analytical Method A.1.2 Experimental ResultsA.2 A Multianalytical Study Unravels Purple Dyeing Processes: The Case of a Historical Dress from the 19th Century; A.2.1 Introduction; A.2.2 Sicilian Noblewoman Dress: Microscopy, Sampling, Experimental Details; A.2.3 Results and Discussion; A.2.4 Conclusions; Curriculum Vitae
• Publisher Details: Cham, Switzerland : Springer
• Publication Date: 2018
• Extent: 1 online resource (xviii, 155 pages), illustrations (some color)
• Subjects: 535.8/46; Raman spectroscopy; Raman effect, Surface enhanced; Spectroscopy and Microscopy; Biological and Medical Physics, Biophysics; Surface and Interface Science, Thin Films; Raman effect, Surface enhanced; Raman spectroscopy; Electronic books
• Languages: English
• ISBNs: 9783030035563; 3030035565
• Related ISBNs: 9783030035556
• Notes: Note: Online resource; title from PDF title page (SpringerLink, viewed December 14, 2018).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.