Malignant brain tumors : state-of-the-art treatment /: state-of-the-art treatment. (2017)

• Record Type: Book
• Further Information: Note: Jennifer Moliterno Gunel, Joseph M Piepmeier, Joachim M. Baehring, editors.
• Editors: Günel, Jennifer Moliterno; Piepmeier, J. M; Baehring, Joachim M
• Contents: Preface; Contents; Contributors; Molecular and Clinical Characterization of Gliomas; 1 Use of Advanced Neuroimaging (fMRI, DTI/Tractography) in the Treatment of Malignant Gliomas; Functional MRI; Task-Based fMRI; Resting State fMRI; Motor Mapping Using fMRI; Supplementary Motor Area; Language fMRI; Language Lateralization; Language Localization; Technical Considerations; Diffusion Tractography; Cortico-Spinal Tract; Arcuate Fasciculus; Visual Projections; Limitations; References; 2 Molecular Neuropathology and the Ontogeny of Malignant Gliomas; Introduction. 2016 WHO Classification-Integrated Diagnostics; Diffuse Astrocytic and Oligodendroglial Gliomas; Histological Profiles of Diffuse Astrocytic and Oligodendroglial Tumors; Diffuse Astrocytic Tumors; Diffuse Oligodendroglial Tumors; Diffuse Oligoastrocytomas; Molecular Profiles of Diffuse Astrocytic and Oligodendroglial Tumors; Isocitrate Dehydrogenase (IDH) Mutations; Co-deletion of 1p/19q; MGMT Methylation Status; Role of Epidermal Growth Factor Receptor (EGFR) Pathway Aberrations; Diffuse Midline Glioma; Ependymal Tumors; Molecular Profiles of Ependymal Tumors; Disclosures; References. 3 Personalized Medicine Through Advanced Genomics; Introduction; Advanced Genomic Technologies; Whole-Genome Sequencing (WGS) and Whole-Exome Sequencing (WES); Bioinformatic Analysis of NGS; Gene Expression Studies; Proteomics; Genomic Approaches to Personalized Medicine; Insights on Malignant Brain Tumors from Genomic Studies; Glioblastoma Multiforme; Medulloblastoma; Meningioma; Tumor Heterogeneity and the Need for Personalized Approaches; Future Directions and Challenges; References; Surgery: Maximizing the Extent of Tumor Resection. 4 The Usefulness of Stereotactic Neuronavigation Along with Intraoperative Imaging in Malignant Brain Tumor Surgery; Introduction; Stereotactic Neuronavigation; Intraoperative Ultrasound (iUS); Intraoperative Magnetic Resonance Imaging (iMRI); Intraoperative Angiography (iA); Summary; References; 5 Mapping the Brain for Primary Brain Tumor Surgery; Introduction; Preoperative Mapping; Preoperative Cortical Methods; Task-Based fMRI (T-fMRI); Rest-Based fMRI (R-fMRI); rTMS: Motor/Language; Preoperative Axonal Mapping; Intraoperative Mapping; Cortical Mapping Under General Anesthesia. Motor: DES Versus Train of Five; Non-motor Functions: Cortico-Cortical Evoked Potentials; Cortical Mapping in Awake Condition; Sensori-Motor Functions; Primary Visual Areas; Language; Spatial Consciousness; Calculation; Double Task; Mentalizing; Other Self-reported Effects of Stimulations; Axonal Mapping Under General Anesthesia; Motor: DES Versus Train of Five; Non-motor Functions: ACEPs; Axonal Mapping in Awake Patients; Motor Functions; Language Function; Visual Functions; Spatial Consciousness; Mentalizing; Mental Calculation; Plasticity and Remapping; Conclusions; References.
• Publisher Details: Cham, Switzerland : Springer
• Publication Date: 2017
• Extent: 1 online resource
• Subjects: 616.99/481; Brain -- Tumors; Brain -- Cancer; HEALTH & FITNESS -- Diseases -- General; MEDICAL -- Clinical Medicine; MEDICAL -- Diseases; MEDICAL -- Evidence-Based Medicine; MEDICAL -- Internal Medicine; Brain -- Cancer; Brain -- Tumors; Medicine & Public Health; Neurosurgery; Surgical Oncology; Electronic books; Electronic book
• Languages: English
• ISBNs: 9783319498645; 3319498649
• Related ISBNs: 9783319498638; 3319498630
• Notes: Note: Includes bibliographical references at the end of each chapters and index.; Note: Online resource; title from PDF title page (SpringerLink, viewed January 11, 2017).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.