Bioactive heterocyclic compound classes. Pharmaceuticals / (2012)

• Record Type: Book
• Further Information: Note: Edited by Jürgen Dinges and Clemens Lamberth.
• Other Names: Dinges, Jürgen; Lamberth, Clemens
• Contents: IINTRODUCTION; ; THE SIGNIFICANCE OF HETEROCYCLES FOR PHARMACEUTICALS AND AGROCHEMICALS; Introduction; Heterocycles as Framework of Biologically Active Compounds; Fine-Tuning the Physicochemical Properties with Heterocycles; Heterocycles as Prodrugs; Heterocycles as Peptidomimetics; Heterocycles as Isosteric Replacement of Functional Groups; Heterocycles as Isosteric Replacement of Alicyclic Rings; Heterocycles as Isosteric Replacement of other Heterocyclic Rings; ; PART I: Neurological Disorders; ; TROPANE-BASED ALKALOIDS AS MUSCARINIC ANTAGONISTS FOR THE TREATMENT OF ASTHMA, OBSTRUCTIVE PULMONARY DISEASE, AND MOTION SICKNESS; Introduction; History; Synthesis; Mode of Action; Structure?Activity Relationships; ; MORPHINONE-BASED OPIOID RECEPTOR AGONIST ANALGESICS; Introduction; History; Synthesis; Mode of Action; Structure?Activity Relationship; ; BARBITURIC ACID-BASED GABA(A) RECEPTOR MODULATORS FOR THE TREATMENT OF SLEEP DISORDER AND EPILEPSY AND AS ANESTHETICS; Introduction; History; Synthesis; Mode of Action; Structure?Activity Relationship; ; PHENOTHIAZINE-BASED DOPAMINE D2 ANTAGONISTS FOR THE TREATMENT OF SCHIZOPHRENIA; Introduction; History; Synthesis; Mode of Action; Structure?Activity Relationships; ; ARYLPIPERAZINE-BASED 5-HT1A RECEPTOR PARTIAL AGONISTS AND 5-HT2A ANTAGONISTS FOR THE TREATMENT OF AUTISM, DEPRESSION, ANXIETY, PSYCHOSIS, AND SCHIZOPHRENIA; Introduction; History; Synthesis; Mode of Action; Structure?Activity Relationship; ; ARYLPIPERIDINE-BASED DOPAMINE D2 ANTAGONISTS/5-HT2A ANTAGONISTS FOR THE TREATMENT OF AUTISM, DEPRESSION, SCHIZOPHRENIA, AND BIPOLAR DISORDER; Introduction; History; Synthesis; Mode of Action; Structure?Activity Relationship; ; DIBENZAZEPINE-BASED SODIUM CHANNEL BLOCKERS FOR THE TREATMENT OF NEUROPATHIC PAIN; Introduction; History; Synthesis; Mode of Action; Structure?Activity Relationships; ; PART II: Cardiovascular Diseases; ; DIHYDROPYRIDINE-BASED CALCIUM CHANNEL BLOCKERS FOR THE TREATMENT OF ANGINA PECTORIS AND HYPERTENSION; Introduction; History; Synthesis; Mode of Action; Structure?Activity Relationship; ; TETRAZOLE-BASED ANGIOTENSIN II TYPE 1 (AT1) ANTAGONISTS FOR THE TREATMENT OF HEART FAILURE AND CONGESTIVE HYPERTENSION; Introduction; History; Synthesis; Mode of Action; Structure?Activity Relationship; ; THIAZIDE-BASED DIURETICS FOR THE TREATMENT OF HYPERTENSION AND GENITOURINARY DISORDERS; Introduction; History; Synthesis; Mode of Action; Structure?Activity Relationship; ; TETRAHYDROPYRANONE-BASED HMG-COA REDUCTASE INHIBITORS FOR THE TREATMENT OF ARTERIAL HYPERCHOLESTEROLEMIA; Introduction; History; Synthesis; Mode of Action; Structure?Activity Relationship; ; PART III: Infectious Diseases; ; ADENINE-BASED REVERSE TRANSCRIPTASE INHIBITORS AS ANTI-HIV AGENTS; Introduction; History; Synthesis; Mode of Action; Structure?Activity Relationship; ; GUANINE-BASED NUCLEOSIDE ANALOGS AS ANTIVIRAL AGENTS; Introduction; History; Synthesis; Mode of Action; Structure?Activity Relationship; ; PENICILLIN AND CEPHALOSPORIN ANTIBIOTICS; Introduction; History; Synthesis; Mode of Action; Structure?Activity Relationships; ; PART IV: Oncology; ; PYRIMIDINE-BASED KINASE INHIBITORS IN CANCER CHEMOTHERAPY; Introduction; History; Synthesis; Mode of Action; Structure?Activity Relationship; ; BENZYL TRIAZOLE-BASED AROMATASE INHIBITORS FOR THE TREATMENT OF BREAST CANCER; Introduction; History; Synthesis; Mode of Action; Structure?Activity Relationship; ; PART V: Inflammation and Gastrointestinal Diseases; ; ACETONIDE-BASED GLUCOCORTICOIDS FOR THE TREATMENT OF ASTHMA, SKIN INFLAMMATION AND DISEASES OF THE EYE; Introduction; History; Synthesis; Mode of Action; Structure?Activity Relationship; ; BENZIMIDAZOLE-BASED H+/K+-ATPASE INHIBITORS FOR THE TREATMENT OF GASTROESOPHAGEAL REFLUX DISEASE; Introduction; History; Synthesis; Mode of Action; Structure?Activity Relationships; ; PART VI: Metabolic Diseases; ; THIAZOLIDINEDIONE-BASED INSULIN SENSITIZERS:PPAR-G AGONISTS FOR THE TREATMENT OF TYPE 2 DIABETES; Introduction; History; Synthesis; Mode of Action; Structure?Activity Relationship; ; INDEX;
• Publisher Details: Place of publication not identified : Wiley-VCH
• Publication Date: 2012
• Extent: 1 online resource (372 pages)
• Subjects: 547.59; Bioactive compounds; Heterocyclic compounds; Pharmaceutical chemistry
• Languages: English
• ISBNs: 9783527664474
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.