Apicomplexan parasites : molecular approaches toward targeted drug development.: molecular approaches toward targeted drug development. (2011)

• Record Type: Book
• Contents: SCREENING, BIOINFORMATICS, CHEMOINFORMATICS, AND DRUG DESIGN; Drug Discovery Approaches towards Anti-Parasitic Agents; (Andreas Rohwer, Richard J. Marhofer, Conor R. Caffrey and Paul M. Selzer); New Bioinformatic Strategies against Apicomplexan Parasites; (Thomas Dandekar and Ke Xiao); Sorting Potential Therapeutic Targets in Apicomplexa; (Jan A. Hiss and Gisbert Schneider); ; Alternatives to Drug Development in Apicomplexa; (Prof. Dr. Theo P.M. Schetters); ; METABOLIC PATHWAYS AND PROCESSES ADDRESSED BY CURRENT DRUG DISCOVERY APPROACHES; ; The Energy Metabolism as an Antimalarial Drug Target; (Esther Jortzik and Katja Becker); Polyamines in Apicomplexan Parasites; (Ingrid B. Muller, Robin Das Gupta, Kai Luersen, Carsten Wrenger and Rolf D. Walter); The Reducing Milieu of Parasitized Cells as a Target of Antimalarial Agents. Methylene Blue as an Ethical Drug; (Peter Meissner, Heike Adler, Karin Fritz-Wolf and R. Heiner Schirmer); Lipids as Drug Targets for Malaria Therapy; (Henri J. Vial, Diana Penarete, Sharon Wein, Sergio Caldarelli, Laurent Fraisse and Suzanne Peyrottes); Targeting Apicoplast Pathways in Plasmodium; (Snober S. Mir, Subir Biswas and Saman Habib); Lipoic Acid Acquisition and Glutathione Biosynthesis in Apicomplexan Parasites; (Janet Storm, Eva-Maria Patzewitz and Sylke Muller); Antimalarial Drugs and Molecules Inhibiting Hemozoin formation; (Uday Bandyopadhyay and Sumanta Dey); Exploiting the Vitamin Metabolism of Apicomplexa as Drug Targets; (Carsten Wrenger and Ingrid B. Muller); ; Vitamin Biosynthetic Pathways, the PLP Synthase Complex, and the Potential for Drugging Protein-Protein Interaction; (Ivo Tews and Irmgard Sinning); Targeting Prokaryotic Enzymes in the Eukaryotic Pathogen Cryptosporidium; (Suresh Kumar Gorla, Corey Johnson, Jihan Khan, Xin Sun, Lisa Sharling; Boris Striepen and Lizbeth Hedstrom); ; DRUG TARGETS IN APICOMPLEXAN PARASITES; Novel Apicomplexan Phosphatases and Immunophilins; as Domain-Specific Drug Targets; (Sailen Barik); Dehydrogenases and enzymes of the mitochondrial electron transport chain as antiapicomplexan drug targets; (Kathleen Zocher, Stefan Rahlfs and Katja Becker); Calcium-dependent protein kinases as drug targets in apicomplexan parasites; (Dominik Kugelstadt, Bianca Derrer, and Barbara Kappes); ; ; Protein Acylation; New Potential Targets for Intervention against Apicomplexa; (Joana M. Santos, Christian Hedberg and Dominique Soldati-Favre); Drugs and Drug Targets in Neospora Caninum and Related Apicomplexans; (Joachim Muller, Norbert Muller and Andrew Hemphill); ; COMPOUNDS; Subversive Substrates of Glutathione Reductases from P. Falciparum-infected Red Blood Cells as Antimalarial Agents; (Elisabeth Davioud-Charvet and Don Antoine Lanfranchi); Ferroquine: a Concealed Weapon (Christophe Biota, Bruno Pradinesb and Daniel Divec); ; Current Aspects of Endoperoxides in Antiparasitic Chemotherapy; (Denis Matovu Kasozi, Stefan Rahlfs and Katja Becker); ; Plasmodium Hsp90 as an Antimalarial Target; (G. Sridhar Prasad and Sailen Barik); Drug Discovery against Babesia and Toxoplasma; (Mohamad Alaa Terkawi and Ikuo Igarashi); Search for Drugs and Drug Targets against Babesia bovis, Babesia bigemina, Babesia caballi, and Babesia (Theileria) equi; (Sabine Bork-Mimm); Orlistat: A Repositioning Opportunity as a Growth Inhibitor of Apicomplexan Parasites?; (Christian Miculka, Hon Tran, Thorsten Meyer, Anja R. Heckeroth, Stefan Baumeister, Frank Seeber and Paul M. Selzer); Recent drug discovery against Cryptosporidium; (Jean-Francois Rossignol, Gilles Gargala, J. Edward Semple and Andrew V. Stachulski); ;
• Publisher Details: Place of publication not identified : Wiley-Blackwell
• Publication Date: 2011
• Extent: 1 online resource (550 pages)
• Subjects: 615.792; Protozoan vaccines -- Development; Apicomplexa
• Languages: English
• ISBNs: 9783527633906
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.