Cigarette smoke toxicity : linking individual chemicals to human diseases /: linking individual chemicals to human diseases. (2011)

• Record Type: Book
• Further Information: Note: Edited by David Bernhard.
• Other Names: Bernhard, David
• Contents: Preface; ; FROM DISCARDED LEAF TO GLOBAL SCOURGE -; THE EXTRAORDINARY HISTORY OF THE ASCENT OF TOBACCO AND ITS MANY MODES OF CONSUMPTION; Public Health Policy and Commercial Interest -; An Uneasy Equilibrium; Blessed Offspring of an Uncouth Land; A Valuable Poison; Sniffing, Chewing, and Smoking; The Development of the Cigarette -; A Perfect Nicotine Delivery System; A Century of Growth; An Epidemic of Disease; Tobacco Manufactured Products -; Multiple Routes to Addiction; History Revisited or Lesson Learned; ; PART I: Cigarette Smoking; ; COMPONENTS OF A CIGARETTE; Introduction; Components of a Cigarette; Generation of Cigarette Smoke; Regulation and Future Perspectives of Cigarette Smoking; ; THE PROCESS OF CIGARETTE SMOKING; Introduction; Bio-Complexity of Pathogenic Components of Smoking; Multiplicity of Tobacco-Induced Diseases; Topography of Cigarette Smoking; How to Define a Human Smoker?; Will there be Standardized Experimental Models to Study Biological Impact by Smoking?; Summary; ; SMOKE CHEMISTRY; Introduction; Cigarette Smoke; Factors Influencing Smoke Chemistry; ; EXPOSURE TO TOBACCO SMOKE; Active Smoking; Secondhand Smoke; Third-Hand Smoke; Quantifying Tobacco Smoke Exposure; Policy Measures for Reducing Tobacco-Related Exposure; ; AN EPIDEMIOLOGICAL APPRAISAL OF SMOKING-RELATED OUTCOMES; Introduction; Meta-Analytical Evidence on Active Smoking; Cancer; Cardiovascular; Fractures; Helicobacter pylori Eradication; Fertility; Ocular Damage; Neurological Effects of Smoking; Rheumatoid Arthritis; Prenatal and Postnatal Effects of Smoking in Children; Review of Meta-Analysis on Secondhand Smoke; Mortality, Biological Aging, and Smoking; Conclusion; ; PART II: Linking Cigarette Smoke Chemicals to Human Diseases and Pathophysiology; ; SMOKING AND CARDIOVASCULAR DISEASES; Introduction; Cardiovascular Diseases; Smoking and CVDs; Summary; ; SMOKING AND CANCER; Introduction; Facts on Smoking and Cancer; Cancer of the Lung; Tobacco Use and Pancreatic Cancer; Tobacco Smoke Combustion Products: Heterocyclic Amines; Smoking, K-ras Mutations and Pancreatic Adenocarcinoma; Interindividual Variation in the Risk of Pancreatic Cancer; Mechanisms of Carcinogenesis by Cigarette Smoke; Summary; ; SMOKING AND COPD AND OTHER RESPIRATORY DISEASES; Introduction; Pathogenesis of COPD; Molecular Determinants of Protease Activity in COPD; Molecular Determinants of Inflammation in COPD; Molecular Determinants of Oxidative Stress in COPD; Activation of Nrf2 by Cigarette Smoke; Exacerbations of COPD; Effects of Cigarette Smoke on Innate Immunity and COPD Exacerbations; Effects of Cigarette Smoke on Asthma; Effects of Cigarette Smoke on Other Respiratory Diseases; Other Molecular Effects of Cigarette Smoke Exposure; Effects of Individual Components of Cigarette Smoke in Lungs; Concluding Remarks; ; SMOKING, INFECTIOUS DISEASES AND INNATE IMMUNE (DYS)FUNCTION; Smoking and Susceptibility to Bacterial Diseases; The Needle in the Haystack; Recognition of Infectious Agents by the Innate Immune Response; The Cholinergic Anti-Inflammatory System; Tobacco Smoking and Netrophil Function; Tobacco Smoking and Bacterial Virulence; Nicotine and Cells of the Adaptive Immune System; Conclusions; ; SMOKING AND REPRODUCTION; Introduction; Smoking and Female Fertility; Reproductive Consequences of Smoking for Men; Consequences of in utero Tobacco Exposure in Later Life of Offspring; ; SMOKING TOBACCO AND GASTROINTESTINAL PATHOPHYSIOLOGY AND DISEASES; Introduction; The Esophagus; Stomach; Intestine; Liver and Pancreas; Summary; ; SMOKING AND ORAL HEALTH; Periodontal Disease; Dental Caries; Oral Cancer; Other Oral Conditions; Other Dental Conditions; Conclusion; ; SMOKING AND EYE DISEASES; Introduction; Smoking and Cataract; Smoking and Glaucoma; Age-Related Macular Degeneration; Association Between Smoking and Age-Related Macular Degeneration; Smoking and Uveitis; Ocular Ischemia; Smoking and Diabetic Retinopathy; Other Ocular Diseases; Conclusions; ; PART III: Prevention and Treatment of Smoking-Induced Diseases; ; SMOKING: PREVENTION AND CESSATION; Strategies for Smoking Prevention and Cessation; Cessation and Risk Reversal: Health Benefits from Giving up Smoking; Smoking Cessation and Gender; Smoking Cessation and Genetics; ; INTERFERING WITH SMOKING-INDUCED PATHOPHYSIOLOGY; Introduction; Cellular Redox Mechanisms Affected by Cigarette Smoke; Perspectives for Prevention and Treatment of Cigarette Smoke-Induced Pathophysiology in Different Tissues; Dietary and Lifestyle Considerations as Related to Pathophysiology in Smokers; Conclusing Remarks; ; PART IV: Summary; ; SUMMARY; Cigarette Smoking and Human Diseases -; A Critical Concluding; Concluding Remarks to this Book
• Publisher Details: Place of publication not identified : Wiley-VCH
• Publication Date: 2011
• Extent: 1 online resource (388 pages)
• Subjects: 616.865071; Cigarette smoke -- Toxicology; Tobacco -- Physiological effect
• Languages: English
• ISBNs: 9783527635337
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.