Bipolar psychopharmacology : caring for the patient.: caring for the patient. (2011)

• Record Type: Book
• Other Names: Akiskal, Hagop S; Tohen, Mauricio
• Contents: List of Contributors. Preface to the Second Edition. Chapter 1 The scope of bipolar disorders (Hagop S. Akiskal ). 1.1 Diagnostic and public health aspects. 1.2 Psychological and social aspects. Chapter 2 Lithium treatment: Focus on long-term prophylaxis (Paul Grof and Mogens Schou ). 2.1 Introduction. 2.2 Cade's pioneering study. 2.3 Discovery of the prophylactic action of lithium. 2.4 Practical issues. 2.5 Are new and better prophylactic agents about to oust lithium? 2.6 Combination treatment. 2.7 Prophylaxis in recurrent depressive disorder. 2.8 The effect of lithium on the patients' suicidal behavior. 2.9 Benefits of prophylactic lithium treatment. 2.10 Conclusion. Chapter 3 Valproate: Clinical pharmacological profile (Charles L. Bowden and Vivek Singh ). 3.1 Historical background. 3.2 Structure–activity relationships. 3.3 Pharmacodynamic properties. 3.4 Pharmacokinetics and metabolic clearance. 3.5 Serum concentration and efficacy. 3.6 Efficacy and indications. 3.7 Efficacy in bipolar disorder. 3.8 Combination strategy in acute mania. 3.9 Prophylaxis in bipolar disorder. 3.10 Treatment of bipolar depression. 3.11 Valproate in treatment of bipolar disorder in children and adolescents. 3.12 Use in bipolar illness comorbid with alcoholism. 3.13 Bipolar disorder comorbid with ADHD. 3.14 Bipolar disorder comorbid with borderline personality disorder. 3.15 Adverse effects. 3.16 Comparative adverse effects. 3.17 Adverse effects in combination therapy, compared with monotherapy. 3.18 Adverse effects by bodily system. 3.19 Summary. Chapter 4 Pharmacological profile and clinical utility of lamotrigine in mood disorders (Marc L.M. van der Loos, Joseph R. Calabrese, Willem A. Nolen and David J. Muzina ). 4.1 Introduction. 4.2 Clinical pharmacology of lamotrigine. 4.3 Lamotrigine and mood disorders. 4.4 Safety. 4.5 Clinical applications for lamotrigine in mood disorders. 4.6 Summary. Chapter 5 Carbamazepine and other anticonvulsants (Heinz Grunze ). 5.1 Introduction. 5.2 Conclusions. Chapter 6 Olanzapine in treatment for bipolar disorder (Mauricio Tohen, Giedra Campbell and Juan-Carlos Gomez ). 6.1 Introduction. 6.2 Rationale in the clinical trial development of olanzapine. 6.3 Efficacy in the treatment of acute mania. 6.4 Efficacy in the treatment of bipolar depression. 6.5 Efficacy in bipolar maintenance/relapse prevention. 6.6 Safety and tolerability. 6.7 Summary. Chapter 7 Haloperidol and other first generation antipsychotics in mania (John Cookson ). 7.1 Introduction. 7.2 Acute tranquillization in mania. 7.3 Sedation is not required for antipsychotics to improve mania. 7.4 Chlorpromazine in mania. 7.5 Haloperidol in mania. 7.6 Hormone changes and mechanisms of antimanic effects of antipsychotics. 7.7 Antipsychotics as mood stabilizers. 7.8 Placebo-controlled studies in mania. 7.9 Recent comparative trials without placebo. 7.10 Pharmacoeconomics. 7.11 Conclusions. Chapter 8 Clinical utility of clozapine in bipolar disorder (V.E. Cosgrove, J.S. Seo, H. Yang and Trisha Suppes ). 8.1 Introduction. 8.2 History. 8.3 Clinical pharmacology of clozapine. 8.4 Clozapine in bipolar disorders. 8.5 Effective pharmacotherapy for bipolar disorder? 8.6 Case studies. Chapter 9 Risperidone and paliperidone in the treatment of bipolar disorder (L. Ivo Caers and Joris Berwaerts ). 9.1 Introduction. 9.2 Oral risperidone in bipolar mania. 9.3 Paliperidone extended release (ER) in bipolar mania. 9.4 Risperidone long-acting injectable (LAI) in the maintenance treatment of bipolar disorder. 9.5 Elements of special interest. 9.6 Summary and conclusions. Chapter 10 Quetiapine in bipolar disorder (Mauricio Kunz, Svante Nyberg and Lakshmi N. Yatham ). 10.1 Introduction. 10.2 Pharmacology. 10.3 Quetiapine in the treatment of acute mania. 10.4 Quetiapine in the treatment of acute bipolar depression. 10.5 Quetiapine in the maintenance treatment of bipolar disorder. 10.6 Safety and tolerability of quetiapine. 10.7 Summary. Chapter 11 Ziprasidone in the treatment of bipolar disorder (Thomas L. Schwartz, Stephen M. Stahl, Elizabeth Pappadopulos and Onur N. Karayal ). 11.1 Introduction. 11.2 Ziprasidone and its proposed mechanism of action. 11.3 Ziprasidone in treatment guidelines. 11.4 Overview of ziprasidone efficacy from clinical trial data. 11.5 Acute manic/mixed episodes. 11.6 Acute depressive episodes. 11.7 Long term maintenance treatment of bipolar disorder. 11.8 Practical guidance on the use of ziprasidone in bipolar disorder. 11.9 Safety and tolerability. 11.10 Treatment of special populations. 11.11 Summary and conclusions. Chapter 12 Aripiprazole in bipolar disorder (Alessandra Nivoli and Eduard Vieta ). 12.1 Aripiprazole and its mode of action. 12.2 Aripiprazole in treatment guidelines. 12.3 Aripiprazole efficacy from clinical trial data. 12.4 Aripiprazole safety and tolerability. 12.5 Treatment of special populations. 12.6 Pharmacogenetics of aripiprazole. Chapter 13 Asenapine in bipolar disorder (Roger S. McIntyre ). 13.1 Introduction. 13.2 Pharmacology. 13.3 Human pharmacokinetics. 13.4 Asenapine: Efficacy in bipolar mania and mixed states. 13.5 Asenapine: Efficacy and tolerability during extension treatment. 13.6 Summary and conclusion. Chapter 14 Complex combination therapy for long-term stability in bipolar disorder (Robert M. Post ). 14.1 Introduction. 14.2 Rationale for complex combination therapy in bipolar illness. 14.3 Principles of building an effective therapeutic regimen. 14.4 Conclusions. Chapter 15 The role of antidepressants in bipolar disorder (Boghos I. Yerevanian ). 15.1 Introduction. 15.2 Tricyclic antidepressants. 15.3 MAO inhibitors. 15.4 SSRIs. 15.5 SNRIs: Venlafaxine, mirtazapine, duloxetine. 15.6 Bupropion. 15.7 Clinical and research implications. Chapter 16 Bipolarity in women: Therapeutic issues (Susan L. McElroy, Lesley M. Arnold and Lori L. Altshuler ). 16.1 Introduction. 16.2 Epidemiology and gender distribution of the bipolar spectrum. 16.3 Gender differences in phenomenology. 16.4 Gender differences in course and outcome. 16.5 Gender differences in comorbidity. 16.6 Bipolar disorder and the reproductive cycle. 16.7 Treatment of bipolar disorder in females. 16.8 Summary. Chapter 17 Pediatric bipolar disorder: The promise of psychopharmacotherapy (Tiffany Thomas and Robert L. Findling ). 17.1 Introduction. 17.2 Lithium. 17.3 Anticonvulsants. 17.4 Antipsychotics. 17.5 Conclusion. Chapter 18 Treatment of bipolar disorder in old age (Kenneth I. Shulman, Nathan Herrmann and Martha Sajatovic ). 18.1 Treatment of bipolar disorder in old age. 18.2 Management of bipolar disorder in the
• Edition: 2nd ed
• Publisher Details: Place of publication not identified : Wiley
• Publication Date: 2011
• Extent: 1 online resource (544 pages)
• Subjects: 616.895061; Manic-depressive illness -- Chemotherapy; Psychopharmacology
• Languages: English
• ISBNs: 9781119956648
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.