Chikungunya virus : advances in biology, pathogenesis, and treatment /: advances in biology, pathogenesis, and treatment. (2016)

• Record Type: Book
• Further Information: Note: Chioma M. Okeoma, editor.
• Editors: Okeoma, Chioma M
• Contents: Preface; Contents; Contributors; Clinical Syndrome and Therapy; Introduction; Acute Stage; Clinical Manifestations and€Symptoms; Arboviral Syndrome; Atypical Manifestations; Neonatal Chikungunya; Clinical Assessment; Diagnosis of€Acute CHIKV Infection; Therapeutic Management; General Principles; Severe Manifestations; Pregnant Women; Neonates and€Children; Prevention; Post-Acute Stage (From D22 to€D90); Clinical Symptoms; Clinical Assessment; Biological Tests and€Imaging; Therapeutic Management; Chronic Stage (After D90); Clinical Symptoms; Biological Tests and€Imaging. Therapeutic Management of€Chronic Inflammatory Rheumatisms Therapeutic Management of€Other Musculoskeletal Disorders (Non-CIR); References; Host Response and€Mechanisms of€Subversion of€Chikungunya; Chikungunya Fever and€Disease Manifestation; Infection and€Disease Pathogenesis: Human and€Animal Models; Cell Targets and€Their Role in€Pathogenesis; Innate Immune Response and€Inflammation; Adaptive Immune Response and€Protection; Challenges and€Limitations to€Fully Understand CHIKV Chronicity; References; Epidemiological History of€Chikungunya Virus; Introduction; Discovery of€CHIKV. Early Outbreaks and€Periodic Detections Re-Emergence of€CHIKV; Ongoing Threat of€CHIKV from€Endemic Areas; Global Expansion; Conclusions; References; Vaccines Against Chikungunya Virus Infection; Introduction; Novel Vaccine Candidates; Live Attenuated Vaccines; Recombinant Viral Vectors; DNA Vaccines; Protein (Virus) Vaccines; Virus-Like Particles (VLPs); Prime-Boost Studies; Immunobiology of€CHIKV Vaccines; Clinical Trials; Attenuated CHIKV Virus Vaccine; Virus-Like Particle Vaccine (VLPs); Recombinant MV-CHIKV; Considerations from€the€Clinical Trials; In Summary. Interaction of€Chikungunya Virus with€the€Mosquito Vector Introduction; Mosquito Biology; Arbovirus Infection of€and€Transmission by Mosquito Vectors; CHIKV Vectors: Distribution, Ecology, Behavior, and€Relative Importance for€Viral Maintenance; Enzootic CHIKV Vectors in€Africa; Urban CHIKV Vectors in€Africa; CHIKV Vectors in€Asia; CHIKV Vectors in€the€Americas; CHIKV Vectors in€Europe; Factors Affecting the€Vector Competence of€Mosquitoes for€CHIKV; Vector Genetics; Molecular Antiviral Mechanisms in€Mosquitoes (RNAi); Role of€Mosquito Microflora.
• Publisher Details: Cham, Switzerland : Springer
• Publication Date: 2016
• Extent: 1 online resource, illustrations
• Subjects: 616.9/1; 610; Medicine; Chikungunya; HEALTH & FITNESS -- Diseases -- General; MEDICAL -- Clinical Medicine; MEDICAL -- Diseases; MEDICAL -- Evidence-Based Medicine; MEDICAL -- Internal Medicine; Chikungunya; Chikungunya virus; Biomedicine; Virology; Epidemiology; Vaccine; Medical -- Epidemiology; Medical -- Immunology; Epidemiology & medical statistics; Immunology; Medical virology; Epidemiology; Vaccines; Medical -- Microbiology; Medical microbiology & virology; Electronic books
• Languages: English
• ISBNs: 9783319429588; 3319429582
• Related ISBNs: 9783319429564; 3319429566
• Notes: Note: Includes bibliographical references.; Note: Print version record.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.