Cardiovascular Safety in Drug Development and Therapeutic Use : New Methodologies and Evolving Regulatory Landscapes /: New Methodologies and Evolving Regulatory Landscapes. (2017)

• Record Type: Book
• Further Information: Note: By J. Rick Turner, Dilip R. Karnad, Snehal Kothari.
• Authors: Turner, J. Rick; Karnad, Dilip R; Kothari, Snehal
• Other Names: École nationale supérieure des beaux-arts (France)
• Contents: The Central Importance of Cardiovascular Safety in Contemporary New Drug Development -- The Biological Basis of Drug Responses -- Cardiovascular Structure, Function, Pathophysiology, & Disease -- The Current Regulatory Landscape -- The "Comprehensive In Vitro Proarrhythmia Assay" Initiative -- The "Early ECG Assessment" Initiative -- The "Submission of Extended Digital ECG Data" Initiative -- Meta-analysis and Meta-methodology -- Current Regulatory Landscapes and their Potential Evolution -- Off-target Blood Pressure Responses to Non-cardiovascular Drugs -- Oncology Drug Development and Therapeutics: Cardiotoxicity Considerations -- Postmarketing Surveillance -- Regulatory Perspectives on General Drug Safety -- Future Directions in Cardiovascular Safety -- References.
• Publisher Details: Cham : Springer International Publishing Imprint Adis
• Publication Date: 2017
• Extent: 1 online resource (XXVI, 333 pages 2 illustrations in color.)
• Subjects: 353.998; Medicine; Cardiology; Pharmacy; Drugs -- Side effects; Drug development; Cardiology; Medicine; Pharmacy; Medical -- Cardiology; Cardiovascular medicine; Medical -- Pharmacology; Pharmacology; Electronic book; Electronic books
• Languages: English
• ISBNs: 3319403478; 9783319403472; 9783319403458; 3319403451
• Notes: Note: Includes bibliographical references at the end of each chapters.; Note: Print version record.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.