Mitochondrial dysfunction in neurodegenerative disorders. (2016)

• Record Type: Book
• Further Information: Note: Amy K. Reeve, Eve M. Simcox, Michael R. Duchen, Doug M. Turnbull, editors.
• Editors: Reeve, Amy Katherine; Simcox, Eve M; Duchen, Michael R; Turnbull, Doug
• Contents: Part I. Mitochondria and Neurodegenerative Disease -- An Introduction to Mitochondria, Their Structure and Functions -- Part II. Mitochondrial Dysfunction: Causes and Effects? -- Neurodegeneration in Mitochondrial Disorders -- The Ageing Brain, Mitochondria and Neurodegeneration -- Mitochondrial Genes and Neurodegenerative Disease -- Mitochondrial Signalling and Neurodegeneration -- Part III. Functional Consequences of Mitochondrial Dysfunction -- Life on the Edge: Determinants of Selective Neuronal Vulnerability in Parkinson's Disease -- Mitochondrial Dynamics and Neurodegeneration -- Mitochondrial Dysfunction and Transport in Demyelinating Disease with Inflammation -- Mitochondria, the Synapse, and Neurodegeneration -- Protein Misfolding and Aggregation: Implications for Mitochondrial Dysfunction and Neurodegeneration -- Mitochondrial Degradation, Autophagy and Neurodegenerative Disease -- The Deleterious Duo of Neurodegeneration: Lysosomes and Mitochondria -- Part IV. Measuring the Contribution of Mitochondrial Dysfunction to Neurodegenerative Disease -- Can We Accurately Model Mitochondrial Dysfunction in Neurodegeneration? -- Mitochondrial Function and Dynamics Imaged In Vivo -- Part V. The Future -- Development of Treatments and Therapies to Target Mitochondrial Dysfunction -- Summary and Conclusions.
• Edition: Second edition
• Publisher Details: Switzerland : Springer
• Publication Date: 2016
• Extent: 1 online resource (xi, 380 pages), illustrations (some color)
• Subjects: 616.8/3; Medicine; Nervous system -- Degeneration; Mitochondrial pathology; HEALTH & FITNESS / Diseases / General; MEDICAL / Clinical Medicine; MEDICAL / Diseases; MEDICAL / Evidence-Based Medicine; MEDICAL / Internal Medicine; Mitochondrial pathology; Nervous system -- Degeneration; Medical -- Biochemistry; Medical -- Neuroscience; Medical -- Internal Medicine; Biochemistry; Neurosciences; Clinical & internal medicine; Neurology; Biochemistry; Neurosciences; Internal medicine; Medical -- Neurology; Neurology & clinical neurophysiology; Electronic books; Electronic books
• Languages: English
• ISBNs: 9783319286372; 3319286374; 3319286358; 9783319286358
• Related ISBNs: 9783319286358
• Notes: Note: Includes bibliographical references at the end of each chapters and index.; Note: Online resource; title from PDF title page (SpringerLink, viewed June 21, 2016).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.