Histone recognition. (2015)

• Record Type: Book
• Further Information: Note: Ming-Ming Zhou, editor.
• Editors: Zhou, Ming-Ming
• Contents: The Bromodomain as the Acetyl-Lysine Binding Domain in Gene Transcription -- PHD Fingers as Histone Readers -- Methyl-Lysine Recognition by the Royal Family Modules: Chromo, Tudor, MBT, Chromo Barrel, and PWWP Domains -- Histone Recognition by WD40 Proteins -- Methyl-Lys Recognition by Ankyrin Repeat Proteins -- Methyl-Arginine Recognition by Tudor Domains -- Histone Recognition by Tandem Modules and Modulation by Multiple PTMs -- Genome-Wide Profiling of Molecular Recognition of Histone PTMs -- BET Bromodomain Inhibition as a Therapeutic Approach in Hematological Malignancies -- Anti-Inflammatory Effects of BET Protein Inhibition Through Modulation of Gene Transcription -- Activating Latent HIV by Inhibiting Bromodomain Proteins -- Small Molecule Modulation of Methyl-Lysine Mediated Interactions.
• Publisher Details: Cham : Springer
• Publication Date: 2015
• Extent: 1 online resource (viii, 282 pages), illustrations (some color)
• Subjects: 572/.66; Medicine; Histones; SCIENCE -- Life Sciences -- Biochemistry; Histones; Histones; Medical -- Genetics; Proteins; Medical genetics; Gene expression; Medical genetics; Electronic books
• Languages: English
• ISBNs: 9783319181028; 3319181025; 3319181017; 9783319181011
• Related ISBNs: 9783319181011
• Notes: Note: Includes bibliographical references and index.; Note: Online resource; title from PDF title page (SpringerLink, viewed June 3, 2015).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.