Atlas of thyroid and neuroendocrine tumor markers. ([2018])

• Record Type: Book
• Further Information: Note: Luca Giovanella, editor.
• Editors: Giovanella, Luca
• Contents: Intro; Foreword; Preface; Contents; Part I: Pathology and Pathobiology; 1: Pathology and Immunohistochemistry in Thyroid Tumors; 1.1 Introduction; 1.2 Immunochemistry in Follicular-Derived Tumors; 1.3 Immunomarkers of Malignancy; 1.4 Prognostic and Predictive Markers; 1.5 Antibodies Directed Against Mutated Genes; References; 2: Pathology of Neuroendocrine Neoplasms: Morphological, Immunophenotypical, and Circulating Molecular Markers; 2.1 Introduction; 2.2 Nomenclature and Classification; 2.2.1 Nomenclature; 2.2.2 Classification of Neuroendocrine Neoplasms. 2.2.2.1 GEP System2.2.2.2 Pulmonary System; 2.3 Morphological Aspects; 2.3.1 Cytological Features; 2.3.1.1 Well-Differentiated Neuroendocrine Neoplasms (Typical Carcinoids, Atypical Carcinoids, Well-Differentiated Neuroendocrine Tumors); 2.3.1.2 Poorly Differentiated Neuroendocrine Carcinomas (NEC) (Large Cell and Small Cell Types); 2.3.2 Histological Features; 2.4 Immunohistochemical Markers; 2.4.1 General Neuroendocrine Markers; 2.4.1.1 Chromogranin A; 2.4.1.2 Synaptophysin; 2.4.1.3 Other Markers. Neuron-Specific Enolase and Other Enzymes Involved in Hormone Synthesis and MetabolismSurface Antigens; Achaete-Scute Homologue 1; 2.4.2 Epithelial Markers; 2.4.3 Markers for Proliferation: Ki67; 2.4.4 Site-Specific Markers; 2.4.4.1 Well-Differentiated NETs; Transcription Factors; Caudal Type Homeobox 2 (CDX2); Thyroid Transcription Factor-1 (TTF-1); Paired Box Gene 8 (PAX8); Insulin Gene Enhancer Binding Protein Isl-1 (Islet 1); Pancreatic and Duodenal Homeobox 1 (PDX1); Amine and Peptide Hormones; 2.4.4.2 Poorly Differentiated NECs. 2.4.5 Prognostic and Predictive (Theranostic) Markers2.4.5.1 Somatostatin Receptors; 2.4.5.2 Cytokeratin 19; 2.4.5.3 CD117; 2.4.5.4 Mismatch Repair Proteins; 2.5 Practical Applications of Immunohistochemistry in Routine Diagnosis; 2.5.1 Cytology; 2.5.2 Histology; 2.6 Circulating Molecular Markers; References; 3: Circulating Biomarkers: Biological Basis, Methods, and Interpretation Criteria; 3.1 Biological Basis and Use of Biomarkers; 3.2 Methods and Quality Requirements for Biomarkers; 3.3 Clinical Performance of Biomarkers; 3.4 Monitoring Cancer Disease by Biomarkers. 3.5 Biomarkers in Neuroendocrine Tumors (NETs)3.6 Diagnostic Performance of Monoanalytes in NETs; 3.7 Perspective: Multianalyte Approaches; References; Part II: Differentiated Thyroid Cancer; 4: Differentiated Thyroid Cancer: Diagnosis, Therapy, and Follow-Up; 4.1 Introduction; 4.2 Epidemiology and Clinical Behavior; 4.2.1 Incidence; 4.2.2 Histology and Clinical Behavior; 4.2.2.1 Papillary Thyroid Carcinoma; 4.2.2.2 Follicular Thyroid Carcinoma; 4.3 Diagnosis; 4.3.1 Presentation; 4.3.2 Ultrasound; 4.3.3 Scintigraphy; 4.3.4 Fine Needle Aspiration Biopsy; 4.4 Treatment.
• Publisher Details: Cham : Springer
• Publication Date: 2018
• Copyright Date: 2018
• Extent: 1 online resource, illustrations (some color)
• Subjects: 616.99/444; Medicine; Thyroid gland -- Tumors; Neuroendocrine tumors; Tumor markers; HEALTH & FITNESS -- Diseases -- General; MEDICAL -- Clinical Medicine; MEDICAL -- Diseases; MEDICAL -- Evidence-Based Medicine; MEDICAL -- Internal Medicine; Neuroendocrine tumors; Thyroid gland -- Tumors; Tumor markers; Medicine & Public Health; Endocrinology; Laboratory Medicine; Nuclear Medicine; Radiotherapy; Pathology; Thyroid Neoplasms -- diagnosis; Biomarkers, Tumor; Neuroendocrine Tumors -- diagnosis; Thyroid Neoplasms -- therapy; Neuroendocrine Tumors -- therapy; Medical -- Laboratory Medicine; Medical -- Radiology & Nuclear Medicine; Medical -- Pathology; Medical laboratory testing & techniques; Nuclear medicine; Radiotherapy; Pathology; Endocrinology; Medical laboratories; Nuclear medicine; Radiotherapy; Pathology; Medical -- Endocrinology & Metabolism; Endocrinology; Electronic books
• Languages: English
• ISBNs: 9783319625065; 3319625063
• Related ISBNs: 9783319625058; 3319625055
• Notes: Note: Includes bibliographical references.; Note: Online resource; title from PDF title page (EBSCO, viewed January 31, 2018).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.