Biomarkers for endometriosis : state of the art /: state of the art. (2017)

• Record Type: Book
• Further Information: Note: Thomas D'Hooghe, editor.
• Other Names: D'Hooghe, Thomas
• Contents: Biomarkers and Endometriosis: The Needto Move Beyond Innovation to Validation; Contents; Contributors; Building Translational Research Infrastructure and Access to Expertise for Biomarker Discovery in Cancer; Introduction; Personalised Medicine and the Use of Biomarkers; The Need for Translational Research Infrastructure; Key Elements of Translational Research Infrastructure and Accessing Expertise; Clinical Use; Management of the Biosample Life Cycle; Quality of Biosamples and the Associated Data; Selection of Collected Biosamples; Accessibility of Biosamples. Future Use of Biosamples Clinical Phenotyping; Biomarker Analysis; A Variety of High-Throughput Platforms for Molecular Analysis; Assay Robustness, Reproducibility and Analytical Validation; Clinical Validity and Clinical Utility; Data Management; Clinical Data; Biosample Metadata; Molecular Data; Interoperable Databases and Information Technology; Data Analysis; Biostatistics; Bioinformatics and System Biology; Verifying Quality and Expertise, Quality Assurance and Quality Control; Quality Assurance of Laboratory Testing; Quality Assurance in Biobanking. Logistics and Operational Support Governance; Ethical Principles for the Use of Biosamples in Research; Use and Reuse of Data in Biomarker Research; Future Trends: New Ways of Working; Industry-Academia Partnerships; Open Innovation Applied to Biomarker Signature Discovery; Collaborative Platforms for Harmonisation and Exchange; Recognising the Benefits of Sharing; Conclusions; References; Biomarkers of Endometrial Cancer; Introduction; Epidemiology; Aetiology and Risk Factors; The Dualistic Model; Clinical Presentation; Investigations; Transvaginal Ultrasound. Hysteroscopy and Endometrial BiopsyStaging; Treatment; Molecular Biology and Genetics of EC; Type 1 (Endometrioid) EC; Type 2 (Serous and Clear Cell) EC; Diagnostic/Screening Markers; Prognostic/Staging Biomarkers; Tissue Biomarkers; Serum Biomarkers; Conclusions and Future Approaches; References; Biomarker Development in Chronic Inflammatory Diseases; Introduction; Biomarkers in Inflammatory Bowel Diseases; Serological Biomarkers of Acute Phase Response; C-reactive Protein; Erythrocyte Sedimentation Rate; Platelets; Serological Markers with Restricted Clinical Use in IBD. Orosomucoid Anti-Saccharomyces cerevisiae Antibodies; Anti-neutrophil Cytoplasmic Antibodies; Anti-glycan Antibodies; Antibody to Outer Membrane Porin (Anti-OmpC); Anti-flagellin Antibodies; Anti-Cbir1; Antibody to Pseudomonas fluorescens: Associated Sequence I2 (Anti-I2); Antibodies to Flagellins A4-Fla2 and Fla-X; Emerging Serological Markers in IBD: Cytokines; Interleukins; TNF-a and TNFa Receptors; Fecal Biomarkers in IBD; Fecal Calprotectin; Fecal Lactoferrin; Biomarkers in Chronic Inflammatory Diseases of Hepatology.
• Publisher Details: Cham : Springer
• Publication Date: 2017
• Extent: 1 online resource
• Subjects: 618.1/075; Medicine; Endometriosis -- Diagnosis; Biochemical markers; MEDICAL -- Gynecology & Obstetrics; Biochemical markers; Medicine & Public Health; Reproductive Medicine; Bioinformatics; Human Genetics; Endometriosis -- diagnosis; Biomarkers; Science -- Life Sciences -- Anatomy & Physiology; Medical -- Genetics; Molecular biology; Medical genetics; Reproductive Medicine; Bioinformatics; Human genetics; Health & Fitness -- Diseases -- Genetic; Reproductive medicine; Electronic books; Electronic book
• Languages: English
• ISBNs: 9783319598567; 3319598562
• Related ISBNs: 9783319598543; 3319598546
• Notes: Note: Includes bibliographical references and index.; Note: Print version record.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.