Sigma receptors : their role in disease and as therapeutic targets /: their role in disease and as therapeutic targets. ([2017])

• Record Type: Book
• Further Information: Note: Sylvia B. Smith, Tsung-Ping Su, editors.
• Editors: Smith, Sylvia B; Su, Tsung-Ping
• Contents: Introduction to sigma receptors: their role in disease and as therapeutic targets / Sylvia B. Smith -- Structural perspectives on sigma-1 receptor function / Assaf Alon, Hayden Schmidt, Sanduo Zheng, Andrew C. Kruse -- A review of the human sigma-1 receptor structure / Felipe Ossa, Jason R. Schnell, José Luis Ortega-Roldan -- Fluorinated pet tracers for molecular imaging of [sigma]1 receptors in the central nervous system / Frauke Weber, Peter Brust, Erik Laurini, Sabrina Pricl, Bernhard Wünsch -- The evolution of the sigma-2 ([sigma2) receptor from obscure binding site to bona fide therapeutic target / Chenbo Zeng, Robert H. Mach -- Sigma 1 receptor and ion channel dynamics in cancer / Olivier Soriani, Rapha︠l Rapetti-Mauss -- Sigma-1 receptors fine-tune the neuronal networks / Shang-Yi Anne Tsai, Tsung-Ping Su -- Pharmacological modulation of the sigma 1 receptor and the treatment of pain / Manuel Merlos, Javier Burgueño, Enrique Portillo-Salido, Carlos Ramón Plata-Salamán [and others] -- Sigma-1 receptor antagonists: a new class of neuromodulatory analgesics / Cristina Sánchez-Fernández, José Manuel Entrena, José Manuel Baeyens [and others] -- Sigma-1 receptors and neurodegenerative diseases: towards a hypothesis of sigma-1 receptors as amplifiers of neurodegeneration and neuroprotection / Linda Nguyen, Brandon P. Lucke-Wold, Shona Mookerjee, Nidhi Kaushal, Rae R. Matsumoto -- Sigma-1 receptor agonists and their clinical implications in neuropsychiatric disorders / Yakup Albayrak, Kenji Hashimoto -- Role of sigma-1 receptor in cocaine abuse and neurodegenerative disease / Yu Cai, Lu Yang, Fang Niu, Ke Liao, Shilpa Buch -- Sigma receptors and substance use disorders / Valentina Sabino, Callum Hicks, Pietro Cottone -- Stimulation of the sigma-1 receptor and the effects on neurogenesis and depressive behaviors in mice / Kohji Fukunaga, Shigeki Moriguchi -- Role of [sigma]1 receptors in learning and memory and Alzheimer's disease-type dementia / Tangui Maurice, Nino Goguadze -- Sigma-1 receptor in motoneuron disease / Renzo Mancuso, Xavier Navarro -- The sigma-1 receptor-A therapeutic target for the treatment of ALS? / Timur A. Mavlyutov, Erin M. Baker, Tasher M. Losenegger, Jaimie R. Kim, Brian Torres [and others] -- The role of sigma1R in mammalian retina / Jing Wang, Xuezhi Cui, Penny Roon, Alan Saul, Sylvia B. Smith -- Peeking into sigma-1 receptor functions through the retina / Timur A. Mavlyutov, Lian-Wang Guo -- The role of sigma 1 receptor as a neuroprotective target in glaucoma / Barbara Mysona, Neil Kansara, Jing Zhao, Kathryn Bollinger.
• Publisher Details: Cham, Switzerland : Springer
• Publication Date: 2017
• Copyright Date: 2017
• Extent: 1 online resource (xiii, 312 pages), illustrations (chiefly color)
• Subjects: 615.7; Medicine; Nervous system -- Degeneration; Sigma receptors; MEDICAL -- Pharmacology; Nervous system -- Degeneration; Sigma receptors; Biomedicine; Biomedicine general; Protein Science; Receptors; Receptors, sigma -- physiology; Neurodegenerative Diseases -- drug therapy; Receptors, sigma -- agonists; Science -- Life Sciences -- Biochemistry; Proteins; Biochemistry; Cell receptors; Medical -- General; Medical research; Electronic books; Electronic books
• Languages: English
• ISBNs: 9783319501741; 3319501747; 3319501720; 9783319501727
• Related ISBNs: 9783319501727; 1489988688
• Notes: Note: Includes bibliographical references and index.; Note: Online resource; title from pdf title page (Springer, viewed March 21, 2017).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.