Carbon nanomaterials for bioimaging, bioanalysis and therapy. (2018)

• Record Type: Book
• Further Information: Note: Edited by Yuen Yung Hui, Huan-Cheng Chang, Haifeng Dong.
• Editors: Hui, Yuen Yung, 1974-; Chang, Huan-Cheng, 1959-; Dong, Haifeng; Zhang, Xueji, 1964-
• Contents: List of Contributors xiii Series Preface xix Preface xxi Part I Basics of Carbon Nanomaterials 1 1 Introduction to Carbon Structures 3 Meng-Chih Su and Yuen Yung Hui 1.1 Carbon Age 3 1.2 Classification 4 1.3 Fullerene 4 1.4 Carbon Nanotubes 6 1.4.1 Structure 6 1.4.2 Electronics 8 1.5 Graphene 10 1.5.1 Structure 10 1.5.2 Electronics 11 1.6 Nanodiamonds and Carbon Dots 12 Acknowledgment 13 References 13 2 Using Polymers to Enhance the Carbon Nanomaterial Biointerface 15 Goutam Pramanik, Jitka Neburkova, Vaclav Vanek, Mona Jani, Marek Kindermann, and Petr Cigler 2.1 Introduction 15 2.2 Colloidal Stability of CNMs 16 2.3 Functionalization of CNMs with Polymers 18 2.3.1 Noncovalent Approaches 18 2.3.2 Covalent Approaches 18 2.4 Influence of Polymers on the Spectral Properties of CNMs 19 2.5 Functionalizing CNMs with Antifouling Polymers for Bioapplications 22 2.6 Functionalization of CNMs with Stimuli‐Responsive Polymers 26 2.6.1 Carbon Nanoparticles with Thermoresponsive Polymers 27 2.6.2 pH‐Responsive Carbon Nanoparticles 27 2.6.3 Redox‐Responsive Carbon Nanoparticles 28 2.6.4 Multi‐Responsive Carbon Nanoparticles 28 2.7 Functionalization of CNMs with Polymers for Delivery of Nucleic Acids 29 2.8 Outlook 32 Acknowledgments 34 References 34 3 Carbon Nanomaterials for Optical Bioimaging and Phototherapy 43 Haifeng Dong and Yu Cao 3.1 Introduction 43 3.2 Surface Functionalization of Carbon Nanomaterials 43 3.3 Carbon Nanomaterials for Optical Imaging 45 3.3.1 Intrinsic Fluorescence of Carbon Nanomaterials 45 3.3.2 Imaging Utilizing Intrinsic Fluorescence Features of Carbon Nanomaterials 46 3.3.3 Imaging with Fluorescently Labeled Carbon Nanomaterials 51 3.4 Carbon Nanomaterials for Phototherapies of Cancer 51 3.4.1 Photothermal Therapy 52 3.4.2 Photodynamic Therapy 53 3.5 Conclusions and Outlook 56 References 56 Part II Bioimaging and Bioanalysis 63 4 High‐Resolution and High‐Contrast Fluorescence Imaging with Carbon Nanomaterials for Preclinical and Clinical Applications 65 John Czerski and Susanta K. Sarkar 4.1 Introduction 65 4.2 Survey of Carbon Nanomaterials 66 4.2.1 Fluorescent Nanodiamonds 66 4.2.2 Carbon Nanotubes 66 4.2.3 Graphene 69 4.2.4 Carbon Nanodots 69 4.3 Fluorescent Properties of FNDs and SWCNTs 69 4.3.1 FNDs 69 4.3.2 SWCNTs 71 4.4 Survey of High‐Resolution and High‐Contrast Imaging 71 4.4.1 General Considerations for Eventual Human Use 71 4.4.2 General Considerations for Achieving High‐Resolution and High‐Contrast Imaging 72 4.4.2.1 Photoacoustic Imaging (PAI) 72 4.4.2.2 X‐ray Computed Tomographic (CT) Imaging 73 4.4.2.3 Magnetic Resonance Imaging (MRI) 73 4.4.2.4 Image Alignment and Drift Correction 74 4.4.3 Preclinical and Clinical Optical Imaging with CNMs 74 4.4.4 Optical Imaging in the Short‐Wavelength Window (~650–950 nm) 74 4.4.4.1 Optical Imaging beyond the Diffraction Limit 75 4.4.4.2 Selective Modulation of Emission 75 4.4.4.3 Time‐Gated Fluorescence Lifetime Imaging 77 4.4.5 Optical Imaging in the Long‐Wavelength Window (~950–1400 nm) 77 4.5 Conclusions 78 References 79 5 Carbon Nanomaterials for Deep‐Tissue Imaging in the NIR Spectral Window 87 Stefania Lettieri and Silvia Giordani 5.1 Introduction 87 5.1.1 Transparent Optical Windows in Biological Tissue 87 5.1.2 Near‐Infrared Imaging Materials 88 5.2 Carbon Nanomaterials for NIR Imaging 89 5.2.1 Biocompatibility of CNMs 90 5.2.2 Fluorescence of CNMs Probes 91 5.2.3 Covalent and Noncovalent Functionalization 91 5.2.4 CNMs as Bioimaging Platforms 91 5.2.4.1 Fullerene 91 5.2.4.2 Carbon Nanotubes 93 5.2.4.3 Graphene Derivatives 99 5.2.4.4 Carbon Dots 100 5.2.4.5 Carbon Nano-onions 102 5.2.4.6 Nanodiamonds 104 5.3 Conclusions and Outlook 105 Acknowledgments 106 References 106 6 Tracking Photoluminescent Carbon Nanomaterials in Biological Systems 115 Simon Haziza, Laurent Cognet, and François Treussart Chapter Summary 115 6.1 Introduction 115 6.2 Tracking Cells in Organisms with Fluorescent Nanodiamonds 116 6.3 Monitoring Inter and Intra Cellular Dynamics with Fluorescent Nanodiamonds 120 6.4 Single‐Walled Carbon Nanotubes: A Near‐Infrared Optical Probe of the Nanoscale Extracellular Space in Live Brain Tissue 127 6.5 Conclusion 131 References 132 7 Photoacoustic Imaging with Carbon Nanomaterials 139 Seunghyun Lee, Donghyun Lee, and Chulhong Kim Chapter Summary 139 7.1 Introduction 139 7.2 Photoacoustic Imaging Systems 140 7.2.1 Photoacoustic Microscopy 141 7.2.2 Photoacoustic Computed Tomography 142 7.3 Photoacoustic Application of Carbon Nanomaterials 145 7.3.1 Carbon Nanomaterials for Photoacoustic Imaging Contrast Agents 146 7.3.2 Carbon Nanomaterials for Multimodal Photoacoustic Imaging 149 7.3.3 Carbon Nanomaterials for Photoacoustic Image‐Guided Therapy 156 7.3.4 Conclusions and Future Perspective 160 Acknowledgments 161 References 162 8 Carbon Nanomaterial Sensors for Cancer and Disease Diagnosis 167 Tran T. Tung, Kumud M. Tripathi, TaeYoung Kim, Melinda Krebsz, Tibor Pasinszki, and Dusan Losic 8.1 Introduction 167 8.2 Detection of VOC by Using Gas/Vapor Sensors for Cancer and Disease Diagnosis 169 8.2.1 Carbon Nanodots (CNDs) and Graphene Quantum Dots (GQDs) for VOC Sensors 171 8.2.2 Carbon Nanotubes (CNTs) for VOC Sensors 173 8.2.3 Graphene for VOC Sensors 176 8.3 Detection of Biomarkers Using Biosensors for Cancer and Disease Diagnosis 179 8.3.1 Carbon Nanodot‐ and Graphene Quantum Dot‐Based Biosensors for Disease Biomarkers Detection 179 8.3.2 Carbon Nanotube‐Based Biosensors for Cancer Biomarker Detection 182 8.3.3 Carbon Nanotube‐Based Biosensors for Disease Biomarker Detection 186 8.3.4 Graphene‐Based Biosensors for Cancer Biomarker Detection 188 8.3.5 Graphene‐Based Biosensors for Disease Biomarker Detection 190 8.4 Conclusions and Perspectives 192 Acknowledgments 193 References 193 9 Recent Advances in Carbon Dots for Bioanalysis and the Future Perspectives 203 Jessica Fung Yee Fong, Yann Huey Ng, and Sing Muk Ng 9.1 Introduction 203 9.2 Fundamentals of CDs 205 9.2.1 Synthesis Approaches 205 9.2.2 Optical Properties 206 9.2.2.1 Absorbance and Photoluminescence (PL) 206 9.2.2.2 Quantum Yield (QY) 210 9.2.2.3 Photoluminescence Origins 210 9.2.2.4 Up‐Conversion Photoluminescence (UCPL) 211 9.2.2.5 Phosphorescence 212 9.2.3 Physical and Chemical Properties 213 9.2.4 Biosafety Assessments 214 9.3 Bioengineering of CDs for Bioanalysis 216 9.3.1 Functionalization Mechanism and Strategies 216 9.3.1.1 Chemical Functionalization 216 9.3.1.2 Doping 217 9.3.1.3 Coupling with Gold Nanoparticles 217 9.3.1.4 Fabrication onto Solid Polymeric Matrices 218 9.3.2 Biomolecules Grafted on CDs as Sensing Receptors 218 9.3.2.1 Deoxyribonuc
• Publisher Details: Hoboken, NJ : John Wiley & Sons
• Publication Date: 2018
• Extent: 1 online resource
• Subjects: 616.07/540284; Nanostructured materials; Carbon; Carbon; Nanostructured materials
• Languages: English
• ISBNs: 1119373441; 9781119373469; 1119373468; 9781119373445; 9781119373476; 1119373476
• Related ISBNs: 9781119373452
• Notes: Note: Includes bibliographical references and index.; Note: Description based on print version record and CIP data provided by publisher; resource not viewed.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.