Evolution of the protein synthesis machinery and its regulation. (2016)

• Record Type: Book
• Further Information: Note: Greco Hernández, Rosemary Jagus, editors.
• Editors: Hernández, Greco; Jagus, Rosemary
• Contents: Preface; Contents; 1 Evolution of tRNAs Was Driven by Entropic Forces; 1 Introduction; 1.1 The tRNA Code; 1.2 tRNA Genes; 2 Entropy in tRNA Molecules; 3 Conclusions; Acknowledgments; References; 2 The Phylogenomic Roots of Translation; 1 Introduction; 2 A Structural Phylogenomic Method to Study the Evolution of Macromolecules; 3 The Early Emergence of Proteins and Metabolism; 4 Insights into the Generation of the First Protein Structures; 5 Late Evolutionary Appearance of First Structural Domains Interacting with RNA; 6 The Co-evolutionary History of Emerging tRNA, Ribosomes and Proteins 7 tRNAs Are Evolutionary Building Blocks of Ribosomes and Genomes8 Conclusions; Acknowledgments; References; 3 Origins and Early Evolution of the Ribosome; 1 The Beginnings: Origins of the PTC and Possible Existence of an RNA World; 1.1 Background; 1.2 RNA World; 1.3 Peptidyl Transferase Center; 2 Toward a Timeline for the Subsequent Evolution of the Translation Machinery; 2.1 Initial Models of Ribosomal RNA Age; 2.2 Accretion Model for Ribosomal RNA History; 2.3 Is the PTC the Oldest Portion of the Ribosome?; 3 Major Events Along the Timeline; 3.1 Homochirality and the Ribosome 3.2 tRNA and the Timeline3.3 Ribosome History Has Implications for the Origin of the Genetic Code; 3.4 Ribosomal Proteins Line the Path to Increasing Complexity; 3.5 Origins of the Dynamic Ribosome; 3.6 Recent Aspects of Ribosome Evolution; 3.6.1 Trigger Factor and Factor Binding Site; 3.6.2 5S rRNA; 4 Summary and Future Studies; References; 4 Evolution of Translational Initiation: From Archaea to Eukarya; 1 Translation Initiation: An Evolutionary Overview; 2 mRNA Features in the Three Domains of Life; 3 Translation Initiation Factors: Conservation and Divergence in the Three Domains of Life 3.1 Universally Conserved TIFs3.2 The Archaeal/Eukaryal Factors; 3.2.1 a/eIF2; 3.2.2 a/eIF6; 4 Conclusions: The Early Evolution of the Translation Initiation Machinery; References; 5 On the Origin and Early Evolution of Translation in Eukaryotes; 1 Introduction; 2 Translation Initiation in the Prokaryotic World; 2.1 mRNA Recruitment in the Last Universal Common Ancestor of Extant Organisms; 3 Translation Initiation in Modern Eukaryotes; 4 The Emergence of Eukaryotic Translation; 4.1 A Closer Look at the Untranslated Regions of Eukaryotic mRNAs 5 The Transition from Prokaryotic to Eukaryotic Translation5.1 What Was the Mechanism of mRNA Recruiting in the Early Eukaryotes?; 6 The Natural History of the Cap Structure, eIF4s and PABP Sheds Light on the Evolution of the Cap-Dependent Translation; 6.1 Origin of the Cap Structure of mRNAs; 6.2 Origin of Eukaryotic Initiation Factors 3, 4G and 4E; 6.3 Origin of PABP and the Evolution of mRNA Circularization; 6.4 Origin of eIF4A and the Evolution of the Scanning Process; 7 A Timeline for the Emergence of the Cap-Dependent Translation Initiation; 8 Concluding Remarks; Acknowledgments
• Publisher Details: Switzerland : Springer
• Publication Date: 2016
• Extent: 1 online resource (ix, 564 pages), illustrations (some color)
• Subjects: 572/.645; 570; Life sciences; Proteins -- Synthesis; Biochemistry; Evolution (Biology); Cytology; Proteins -- Synthesis; SCIENCE / Life Sciences / Biochemistry; Science -- Life Sciences -- Evolution; Science -- Life Sciences -- Biology -- Molecular Biology; Science -- Life Sciences -- Biochemistry; Science -- Life Sciences -- Zoology -- General; Evolution; Cellular biology (cytology); Botany & plant sciences; Zoology & animal sciences; Proteins; Electronic books
• Languages: English
• ISBNs: 9783319394688; 3319394681
• Related ISBNs: 9783319394671
• Notes: Note: Online resource; title from PDF title page (SpringerLink, viewed August 24, 2016).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.