Nanooncology : engineering nanomaterials for cancer therapy and diagnosis /: engineering nanomaterials for cancer therapy and diagnosis. (2018)

• Record Type: Book
• Further Information: Note: Gil Gonçalves, Gerard Tobias, editors.
• Editors: Gonçalves, Gil; Tobias, Gerard
• Contents: Intro; Contents; Gold Nanoparticles for Imaging and Cancer Therapy; 1 Introduction; 2 Synthesis of Gold Nanoparticles for Biomedical Applications; 2.1 Direct Reduction: The Turkevitch Method; 2.2 Seed-Mediated Growth for Smaller and Narrower Particle Size Distributions; 2.3 Syntheses Taking Place in Organic Media; 2.4 Au NPs Purification Prior to Coatings and Functionalization; 2.5 Ligand-Free Au NP Suspensions; 2.6 Surface Treatment of Au NPs; 2.7 Cell Toxicity of Au NPs: In Vitro Studies; 3 Principles of Physical Interactions Between Photons and High-Z Elements. 4 Impact of Radiation and Au-Mediated Radiosensitization Products on Cells and Tissues4.1 The Physical Phase; 4.2 The Chemical Phase; 4.3 Measurement of Physical and Chemical Impact of Au NPs on DNA; 4.4 The Biological Phase; 5 Performance of Au NPs as X-Ray Computed Tomography Contrast Agents; 5.1 Attenuation of X-Rays by High-Z Elements; 5.2 Conventional Iodinated Contrast Agents; 5.3 Blood-Pool Contrast Agents; 5.4 Au-Based Blood-Pool Agents; 6 Performance of Gold Nanoparticles as Radiosensitizers in Oncology; 6.1 Main Mechanisms of Radiosensitization. 6.2 Au NPs as Radiosensitizers in External Beam Therapy6.3 Dose Simulations Have Confirmed a Good Match Between Au NPs and Brachytherapy Sources; 6.4 Radioactive Au NPs; 6.5 Current Status of Au NPs as Radiosensitizers for Clinical Applications; 7 Biodistribution, Clearance and in Vivo Toxicity; 7.1 Biodistribution and Clearance Routes of Gold Nanoparticles; 7.2 The Intravascular Injection Route; 7.3 The Intratumoral Injection Route; 7.4 In Vivo Toxicity Studies; 8 Perspectives: Current Status of Au NPs in Clinical Trials; 9 Conclusion; References. Liposomes-Based Nanoparticles for Cancer Therapy and Bioimaging1 Introduction; 1.1 Liposome Composition; 2 Cancer Therapy; 2.1 Drug Delivery System; 2.2 Liposomes in Gene Delivery; 2.3 Targeted Delivery; 3 Bioimaging; 3.1 Image-Guided Drug Delivery; 4 Conclusion; References; Quantum Dots for Cancer Therapy and Bioimaging; 1 Semiconductor Quantum Dots; 1.1 QDs for Tumor Imaging; 1.2 QDs in Cancer Therapy; 1.3 Limitations and Future Perspectives; 2 Silver Chalcogenide Quantum Dots; 2.1 Silver Sulfide (Ag2S) QDs; 2.2 Silver Selenide (Ag2Se) QDs; 2.3 Silver Telluride (Ag2Te) QDs. 2.4 Limitations and Future Perspectives3 Carbon Quantum Dots; 3.1 CDs for Cancer Bioimaging; 3.2 CDs for Cancer Therapy; 4 Silicon Quantum Dots; 4.1 Silicon Quantum Dots for Bioimaging Applications; 4.2 Silicon Quantum Dots for Drug Delivery and Cancer Therapy; 5 Black Phosphorus Quantum Dots (BP QDs); 6 Germanium Quantum Dots (Ge QDs); 7 Semiconducting Polymer Dots; 7.1 Cancer Cell-Specific Imaging and in Vivo Tumor Imaging; 7.2 Pdots-Based Cancer Therapy; 7.3 Non-conjugated Pdots and Their Biomedical Applications; 8 Final Remarks and Future Perspective; References.
• Publisher Details: Cham, Switzerland : Springer
• Publication Date: 2018
• Extent: 1 online resource (vi, 455 pages), illustrations (some color)
• Subjects: 616.99/4; Materials science; Oncology -- Technological innovations; Nanomedicine; Nanotechnology; Biomedical engineering; Oncology; Biomaterials; Toxicology; HEALTH & FITNESS -- Diseases -- General; MEDICAL -- Clinical Medicine; MEDICAL -- Diseases; MEDICAL -- Evidence-Based Medicine; MEDICAL -- Internal Medicine; Nanomedicine; Technology & Engineering -- Engineering (General); Medical -- Oncology; Technology & Engineering -- Material Science; Medical -- Pharmacology; Biomedical engineering; Oncology; Materials science; Pharmacology; Technology & Engineering -- Nanotechnology & MEMS; Nanotechnology; Materials Science; Nanotechnology; Biomedical Engineering; Cancer Research; Biomaterials; Pharmacology/Toxicology; Electronic books
• Languages: English
• ISBNs: 9783319898780; 3319898787; 3319898779; 9783319898773
• Related ISBNs: 9783319898773
• Notes: Note: Online resource; title from PDF title page (SpringerLink, viewed June 5, 2018).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.