Chimerism : a clinical guide /: a clinical guide. (2018)

• Record Type: Book
• Further Information: Note: Nicole L. Draper, editor.
• Editors: Draper, Nicole L
• Contents: Intro; Preface; Contents; Contributors; Part I: Causes of Chimerism in Humans; Chapter 1: Fertilization and Early Embryonic Errors; Introduction; Detection of Chimerism; Mechanisms of Abnormal Fertilization; Diandric Chimerism; Androgenetic Chimerism; Digynic Chimerism; Mechanisms of Abnormal Early Embryogenesis; Tetragametic Chimerism; Postzygotic Splitting; Mosaicism; Summary; References; Chapter 2: Pregnancy and Multiple Gestations; Introduction; Chimerism as a Result of Pregnancy; Chimerism as a Result of Multiple Gestations; Persistence of Chimerism. Clinical Implications of Chimerism in Multiple GestationsSummary; References; Chapter 3: Transplantation and Transfusion; Introduction; Tissue Transplantation; Solid Organ Transplantation; Heart; Kidney; Liver; Lung; Pancreas; Intestine; Hematopoietic Stem Cell Transplantation; Blood Product Transfusion; Transfusion-Associated Microchimerism; Trauma; Combat; HIV; Immunocompetent; Importance of Microchimerism; References; Part II: Clinical Identification and Consequences of Chimerism; Chapter 4: Relationship Testing and Forensics; Introduction; Consequences of Chimerism in Forensics. Consequences of Chimerism in Relationship TestingCase Study: A Chimeric Father's False Paternity Exclusion; Logic in Testing the Paternity of a Chimeric Alleged Father; Case Conclusions; Case Study: Identifying a Chimeric Child; Case Conclusions; Recommendations for Relationship and Forensic DNA Testing of Undiagnosed Chimera; Limitations to Current DNA Testing Systems; Alternative/Reflexive Testing Recommendations; Future Research; References; Chapter 5: Prenatal Genetic Testing and Screening; Introduction and Definitions; Types of Pregnancy-Related Chimerism. Maternal Cells in the Fetus: Maternal Microchimerism (MMC)Fetal Cells in the Mother: Fetal Microchimerism (FMC); Cell-Free Fetal DNA in Maternal Plasma: Transient Acellular Fetal Microchimerism; Pregnancies Resulting from Early Embryonic Chimerism; Chimerism and Mosaicism: Distinct Entities with Different Genetic Diagnostic Implications; Benefits and Pitfalls of Chimerism for Prenatal Genetic Testing; Cell-Based Noninvasive Prenatal Genetic Testing; Chimerism and Cell-Free DNA-Based Testing; Chimerism in Multiple Pregnancies; Monozygotic Twins; Dizygotic Twins. Fetal Microchimerism and Obstetric or Maternal PathologyNon-chimeric Fetal Cells Accessible for Noninvasive Prenatal Diagnosis; Conclusion; References; Chapter 6: Blood Typing Discrepancies; Introduction; Blood Typing Tests; Red Blood Cell Typing; Secretor Studies; HLA Typing; Molecular Studies; Nature and Investigation of Blood Typing Discrepancies; Clinical Investigation; Laboratory Testing; Molecular Studies; Clinical Cases; Twin Chimerism; Dispermic Chimerism; Tetragametic Chimerism; Feto-maternal Microchimerism; Hematopoietic Transplantation Associated; Transfusion Associated.
• Publisher Details: Cham, Switzerland : Springer
• Publication Date: 2018
• Extent: 1 online resource (xi, 200 pages), illustrations (some color)
• Subjects: 616/.042; Medicine; Chimerism; HEALTH & FITNESS -- Diseases -- General; MEDICAL -- Clinical Medicine; MEDICAL -- Diseases; MEDICAL -- Evidence-Based Medicine; MEDICAL -- Internal Medicine; Chimerism; Medicine & Public Health; Hematology; Blood Transfusion Medicine; Medical -- Hematology; Haematology; Hematology; Blood transfusion; Electronic books
• Languages: English
• ISBNs: 9783319898667; 3319898663
• Related ISBNs: 9783319898650; 3319898655
• Notes: Note: Online resource; title from PDF title page (SpringerLink, viewed June 29, 2018).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.