Planning and analyzing clinical trials with composite endpoints. ([2017])

• Record Type: Book
• Further Information: Note: Geraldine Rauch, Svenja Schüler, Meinhard Kieser.
• Authors: Rauch, Geraldine; Schüler, Svenja; Kieser, Meinhard
• Contents: Preface -- Contents -- Part I General Introduction to Composite Endpoints -- 1 Definition and Rationale -- 2 Challenges of Composite Endpoints -- 3 Guideline View -- Recommendations and Requirements -- 4 Clinical Trial Examples -- Part II Confirmatory Test Problem for a Single (Composite) Endpoint -- 5 The Single-Stage Design -- 6 Group-Sequential and Adaptive Designs -- 7 Related Software Code -- Part III Confirmatory Multiple Test Problem -- 8 Correlation Between Test Statistics -- 9 The Single-Stage Design -- 10 Group-Sequential and Adaptive Designs -- 11 Related Software Code -- Part IV Confirmatory Test Problem for a Weighted Composite Endpoint -- 12 Weighted Binary Composite Endpoint -- Weighted Time-to-Event Composite Endpoint -- 14 OtherWeighted Effect Measures -- 15 Related Software Code -- Part V Descriptive and Confirmatory Evaluation of the Components -- 16 Descriptive Analysis of the Components -- 17 Supplementary Confirmatory Analyses of the Components -- 18 Related Software Code -- Part VI Illustrating Clinical Trial Examples -- 19 Clinical Trial Examples with Binary (Composite) Endpoints -- 20 Clinical Trial Examples with (Composite) Time-to-Event Endpoints.
• Publisher Details: Cham, Switzerland : Springer
• Publication Date: 2017
• Extent: 1 online resource
• Subjects: 610.72/7; Statistics; Clinical trials -- Statistical methods; HEALTH & FITNESS -- Holism; HEALTH & FITNESS -- Reference; MEDICAL -- Alternative Medicine; MEDICAL -- Atlases; MEDICAL -- Essays; MEDICAL -- Family & General Practice; MEDICAL -- Holistic Medicine; MEDICAL -- Osteopathy; Clinical trials -- Statistical methods; Science -- Life Sciences -- General; Medical -- Pharmacy; Life sciences: general issues; Pharmaceutical technology; Statistical methods; Pharmaceutical technology; Medical -- Biostatistics; Probability & statistics; Electronic books
• Languages: English
• ISBNs: 9783319737706; 3319737708; 3319737694; 9783319737690
• Related ISBNs: 9783319737690
• Notes: Note: Online resource; title from PDF title page (EBSCO, viewed May 31, 2018).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.