Coupling and decoupling of diverse molecular units in glycosciences. ([2018])

• Record Type: Book
• Further Information: Note: Zbigniew J. Witczak, Roman Bielski, editors.
• Editors: Witczak, Zbigniew J, 1947-; Bielski, Roman, 1946-
• Contents: Synthesis of N-linked glycopeptides using convergent enzymatic glycosylation combined with SPPS.- Synthetic Antitumor Vaccines through Coupling of Mucin Glycopeptide Antigens to Proteins.- Recent Advances in the Stereochemical Outcome of Multi Component Reactions Involving Convertible Isocyanides.- Glycoconjugate-based inhibitors of Mycobacterium tuberculosis GlgE.- Selective Transformations of the Anomeric Centre in Water Using DMC and Derivatives -- [3, 3]-Sigmatropic Rearrangement as a Powerful Synthetic Tool on Skeletal Modification of Unsaturated Sugars -- Recognition of thiols in coupling reactions to organic and carbohydrate acceptors.- Chemical approaches toward neurodegenerative disease prevention: the role of coupling sugars to phenolic biomolecular entities -- Probing for Trypanosoma cruzi cell surface glycobiomarkers for the diagnosis and follow-up of chemotherapy of Chagas disease -- Syntheses and Functions Glycosaminoglycan Mimicking Polymers.- Methods for the high resolution analysis of glycoconjugates.- Masking Strategies for the Bioorthogonal Release of Anticancer Glycosides.- Example of Sacrificial Unit Using Two Different Click Reactions in Coupling and Decoupling (CAD) Chemistry.- Increased efficacy of NKT cell adjuvanted peptide vaccines through chemical conjugation.
• Publisher Details: Cham, Switzerland : Springer
• Publication Date: 2018
• Extent: 1 online resource, illustrations
• Subjects: 616.07/56; Chemistry; Clinical chemistry; Glycosidases; Biochemistry; Carbohydrates; Bioorganic chemistry; Biomaterials; HEALTH & FITNESS -- Diseases -- General; MEDICAL -- Clinical Medicine; MEDICAL -- Diseases; MEDICAL -- Evidence-Based Medicine; MEDICAL -- Internal Medicine; Clinical chemistry; Glycosidases; Science -- Chemistry -- Organic; Technology & Engineering -- Material Science; Carbohydrates; Biochemistry; Materials science; Science -- Chemistry -- Clinical; Chemistry; Medicinal Chemistry; Carbohydrate Chemistry; Bioorganic Chemistry; Biomaterials; Glycoconjugates -- chemical synthesis; Glycomics -- methods; Metabolic Engineering -- methods; Electronic books
• Languages: English
• ISBNs: 9783319655871; 3319655876
• Related ISBNs: 9783319655864; 3319655868
• Notes: Note: Includes bibliographical references.; Note: Online resource; title from PDF title page (EBSCO, viewed November 28, 2017).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.