Oncoimmunology : a practical guide for cancer immunotherapy /: a practical guide for cancer immunotherapy. (2018)

• Record Type: Book
• Further Information: Note: Laurence Zitvogel, Guido Kroemer, editors.
• Editors: Zitvogel, L (Laurence); Kroemer, Guido
• Contents: Fundamental bases:Immunology for the non immunologist: Cellular and molecular bases of cancer immunosurveillance.-Innate immunity/NK in cancer immunosurveillance.-Biology of regulatory T cells.-Adenosine, P2R receptors.-Plasmacytoid DC dysfunctions in cancer.-Chemotherapy and MDSC.-Biology of Myeloid Derived Suppressor Cells.-T cell fitness/polarization for antitumor immune responses.-Tumor associated antigens and neoantigens.-Tumor associated antigens and neoantigens.-Immunization with peptides.-Immunogenic cell death and chemotherapy.-Breakthrough or advanced status of approaches:Cancer vaccines in HPV malignancies.-Innate sensing of tumors and TLR agonists.-DC-based cancer vaccines in melanoma.-DC-based vaccines in breast cancer.-T cell-based immunotherapies: CAR-T and TCR engineered T cells.-IDO and TDO-based inhibition in cancer. -FDA-EMA approval of I-O:Tumor-specific antibodies.-Anti-CTLA4 Abs.-Bispecific anti-CD3xCD19 antibodies.-Combination of ICB in MM.-Oncolytic viruses.-Bacillus Calmette-Guérin and mycobacterial cell wall nucleic acid complexes in the treatment of non-muscle-invasive bladder cancer .-The immunoscore.-PDL-1 and other immunological diagnosis tools.-Developping fields:The development of anti-41BB, Lag3, Anti-OX40, anti-ICOS, anti-GITR Ab.-mRNA-based vaccination.-Links between tumor genetics and immunotherapy.-Local immunotherapies of cancer.-Preventive DC-based cancer vaccines.-Gut microbiota/oncomicrobiotics in cancer therapeutics.-Strategies to reduce intratumoral Treg.-Cold versus hot tumors.-Immunopathology: an emerging field.-Changes in Clinical Practice:Side effects of I-O.-The clinical armamentarium in melanoma.-The clinical armamentarium in kidney cancers.-The clinical armamentarium in lung cancers.-The clinical armamentarium in prostate cancers.-Challenges of O-I for breast, ovarian, and non MSI colon cancers.-Challenges in colon cancers.-Current status of O-I in hematologic malignancies.-Glioma and I-O.-Assessing affinity and avidity of TCRs.-Immunomonitoring studies.
• Publisher Details: Cham, Switzerland : Springer
• Publication Date: 2018
• Extent: 1 online resource
• Subjects: 616.99/406; Medicine; Cancer -- Immunotherapy; HEALTH & FITNESS -- Diseases -- General; MEDICAL -- Clinical Medicine; MEDICAL -- Diseases; MEDICAL -- Evidence-Based Medicine; MEDICAL -- Internal Medicine; Cancer -- Immunotherapy; Medical -- Immunology; Medical -- Oncology; Immunology; Oncology; Oncology ; Immunology; Oncology; Electronic books
• Languages: English
• ISBNs: 9783319624310; 3319624318; 9783319624303
• Related ISBNs: 9783319624303; 331962430X
• Notes: Note: Online resource; title from PDF title page (EBSCO, viewed December 27, 2017).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.