Cardiac regeneration. (2017)

• Record Type: Book
• Further Information: Note: Masaki Ieda, Wolfram-Hubertus Zimmermann, editors.
• Editors: Ieda, Masaki; Zimmermann, Wolfram-Hubertus
• Contents: ""Preface""; ""Contents""; ""1: Past and Future of Cell-Based Heart Repair""; ""1.1 Introduction""; ""1.2 Cell Therapy for Cardiac Repair""; ""1.2.1 Skeletal Myoblasts""; ""1.2.2 Bone Marrow-Derived Stem Cells""; ""1.2.3 Endothelial Progenitors""; ""1.2.4 Mesenchymal Stem Cells""; ""1.2.5 Endogenous Cardiac Stem Cells""; ""1.2.5.1 C-kit + Cardiac Progenitors""; ""1.2.5.2 Cardiosphere and Cardiosphere-Derived Cells""; ""1.2.5.3 Side Population Cells""; ""1.2.5.4 Sca1+ Cardiac Progenitors""; ""1.2.5.5 Islet1+ Cardiac Progenitors""; ""1.2.5.6 Epicardial Progenitors"" ""1.2.6 ES-Derived Cardiomyocytes""""1.2.7 Induced Pluripotent Stem Cells and Reprogramming""; ""1.2.7.1 iPSCs""; ""1.2.7.2 Direct Reprogramming into Cardiomyocytes""; ""1.3 Future of Cell Therapy""; ""References""; ""2: Progenitor Cells from the Adult Heart""; ""2.1 Phenotype and Characteristics of eCSCs""; ""2.1.1 c-kitpos Stem and Progenitor Cells""; ""2.1.2 Sca-1pos and Side Population Progenitor Cells""; ""2.2 Cardiac Differentiation Potential of eCSCs""; ""2.3 The Controversy""; ""2.4 Origin of eCSCs""; ""2.5 Impact of Ageing and Senescence on eCSCs"" ""2.6 Therapeutic Targets to Activate eCSCs and Reverse the Senescent, Dysfunctional eCSC Phenotype""""References""; ""3: Epicardial Progenitors in the Embryonic and Adult Heart""; ""3.1 Epicardial Development Across Species""; ""3.2 EPDC Derivatives and Epicardial Heterogeneity""; ""3.2.1 Epicardium Contribution to Coronary Endothelial Cells""; ""3.2.2 Epicardial Contribution to Cardiomyocytes""; ""3.2.3 Epicardial Contribution to Fat Cells""; ""3.3 The Epicardium as a Signaling Center in the Developing Heart"" ""3.3.1 Epicardial Signals Promoting Cardiomyocyte Proliferation""""3.3.2 Epicardial Signals Directing Coronary Angiogenesis""; ""3.3.3 Other Epicardial Signals Contributing to Heart Development""; ""3.4 Adult Epicardium""; ""3.4.1 Physiological Role of the Epicardium in Homeostatic Conditions""; ""3.4.2 The Epicardium to Regenerate the Adult Heart""; ""3.5 Human Epicardium""; ""References""; ""4: Generation and Application of Human Pluripotent Stem Cell-Derived Cardiomyocytes""; ""4.1 Introduction""; ""4.2 Applications""; ""4.2.1 Regenerative Medicine"" ""4.2.2 Biological Pacemaker Development""""4.2.3 Understanding of Human Cardiac Development""; ""4.2.4 Disease Modeling""; ""4.2.5 Drug Discovery, Pharmacogenomics, and Cardiotoxicity Screening""; ""4.3 Cardiomyogenesis during Mammalian Heart Development""; ""4.4 Control of the Pluripotent State""; ""4.5 Human Pluripotent Growth Media""; ""4.6 Priming for Cardiac Differentiation""; ""4.7 Maintenance of hiPSC-Derived Mesodermal Intermediates and Cardiac Progenitor Cells""; ""4.8 Directed Cardiac Differentiation of Human Pluripotent Stem Cells""
• Publisher Details: Cham : Springer
• Publication Date: 2017
• Extent: 1 online resource
• Subjects: 616.1/2; Medicine; Cardiology; Heart -- Diseases -- Treatment; Regenerative medicine; Biomedical engineering; Cardiovascular system; HEALTH & FITNESS -- Diseases -- General; MEDICAL -- Clinical Medicine; MEDICAL -- Diseases; MEDICAL -- Evidence-Based Medicine; MEDICAL -- Internal Medicine; Cardiology; Heart -- Diseases -- Treatment; Regenerative medicine; Science -- Life Sciences -- Cytology; Science -- Life Sciences -- Biology -- Molecular Biology; Medical -- Cardiology; Cellular biology (cytology); Cardiovascular medicine; Medical research; Medical -- Allied Health Services -- Medical Technology; Biomedical engineering; Biomedicine; Human Physiology; Biomedical Engineering/Biotechnology; Regenerative Medicine/Tissue Engineering; Stem Cells; Cardiology; Molecular Medicine; Electronic books
• Languages: English
• ISBNs: 9783319561066; 3319561065
• Related ISBNs: 9783319561042; 3319561049
• Notes: Note: Includes bibliographical references.; Note: Online resource; title from PDF title page (EBSCO, viewed November 3, 2017).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.