Extended abstracts Fall 2015 : Biomedical Big Data ; Statistics for Low Dose Radiation Research /: Biomedical Big Data ; Statistics for Low Dose Radiation Research. (2017)

• Record Type: Book
• Further Information: Note: Elizabeth A. Ainsbury, M. Luz Calle, Elisabeth Cardis, Jochen Einbeck, Guadalupe Gómez, Pere Puig, editors.
• Editors: Ainsbury, Elizabeth A; Calle, M. Luz; Cardis, Elisabeth Marcelle; Einbeck, Jochen; Gómez, Guadalupe; Puig, Pere
• Contents: Part I Biomedical Big Data; Extreme Observations in Biomedical Data; 1 Introduction; 2 Methods; 3 Application to Data in Autism Multiplex Families; 4 Application to Gene Expression Data in Cancer; References; An Ordinal Joint Model for Breast Cancer; 1 Introduction; 2 A Bayesian Joint Model for Ordinal Longitudinal and Left Truncated Survival Data; 3 Breast Cancer and Mammographic Breast Density; References; Sample Size Impact on the Categorisation of Continuous Variables in Clinical Prediction; 1 Motivation; 2 Methods. 2.1 Categorisation Proposal Based on GAM with P-Spline Smoothers; 2.2 Optimal Categorisation Based on the Maximisation of the AUC; 3 Simulation Study; 3.1 Scenarios and Set Up; 3.2 Results; 4 Conclusions; References; Integrative Analysis of Transcriptomics and Proteomics Data for the Characterization of Brain Tissue After Ischemic Stroke; 1 Introduction and Objectives; 2 Methods; 3 Results; 4 Conclusions; References; Applying INAR-Hidden Markov Chains in the Analysis of Under-Reported Data; 1 Introduction; 2 The Model; 2.1 Parameter Estimation; 2.2 Reconstruction of the Underlying Process. 2.3 Model Selection and Goodness of Fit; 3 Example of Application; References; Joint Modelling for Flexible Multivariate Longitudinal and Survival Data: Application in Orthotopic Liver Transplantation; 1 Introduction; 2 Orthotopic Liver Transplantation Data; 3 Two-Stage Model Based Proposal; 3.1 Stage 1: Flexible Multivariate Longitudinal Data; 3.2 Stage 2: Survival Model; 4 Conclusions; References; A Multi-state Model for the Progression to Osteopenia and Osteoporosis Among HIV-Infected Patients; 1 Motivation; 2 Multi-state Model; 2.1 Notation; 2.2 Estimation Method; 3 Results. 3.1 Descriptive Analysis; 3.2 Estimated Transition Probabilities; 4 Discussion; References; Statistical Challenges for Human Microbiome Analysis; 1 Introduction; 2 Methods; 3 Results; 4 Conclusions; References; Integrative Analysis to Select Genes Regulated by Methylation in a Cancer Colon Study; 1 Introduction and Objectives; 2 Methods for L-Pattern Selection; 2.1 Gene Selection Based on Conditional Mutual Information; 2.2 Gene Selection Based on Spline Regression; 3 Results and Application: Selecting L-Shaped Genes from a Genome-Wide Analysis of Colorectal Cancer. 3.1 Results Using the Conditional Mutual Information Approach; 3.2 Results Using Splines Regression to Select Genes; 4 Discussion and Conclusions; References; Topological Pathway Enrichment Analysis of Gene Expression in High Grade Serous Ovarian Cancer Reveals Tumor-Stoma Cross-Talk; 1 Introduction; 2 Methods; 3 Results; 4 Discussion; 5 Conclusion; References; Part II Statistics for Low Dose Radiation Research; Biological Dosimetry, Statistical Challenges: Biological Dosimetry After High-Dose Exposures to Ionizing Radiation; References.
• Publisher Details: Cham, Switzerland : Birkhäuser
• Publication Date: 2017
• Extent: 1 online resource
• Subjects: 610.1/51; 519.5; Statistics; Biomedical engineering -- Mathematical models; HEALTH & FITNESS -- Holism; HEALTH & FITNESS -- Reference; MEDICAL -- Alternative Medicine; MEDICAL -- Atlases; MEDICAL -- Essays; MEDICAL -- Family & General Practice; MEDICAL -- Holistic Medicine; MEDICAL -- Osteopathy; Biomedical engineering -- Mathematical models; Mathematics -- Applied; Science -- Life Sciences -- General; Maths for scientists; Life sciences: general issues; Statistical methods; Medical -- Biostatistics; Probability & statistics; Electronic books
• Languages: English
• ISBNs: 9783319556390; 3319556398
• Related ISBNs: 9783319556383; 331955638X
• Notes: Note: Includes bibliographical references at the end of each chapters.; Note: Online resource; title from PDF title page (SpringerLink, viewed May 15, 2017).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.