Oxidative stress in human reproduction : shedding light on a complicated phenomenon /: shedding light on a complicated phenomenon. (2017)

• Record Type: Book
• Further Information: Note: Ashok Agarwal, Rakesh Sharma, Sajal Gupta, Avi Harlev, Gulfam Ahmad, Stefan S. du Plessis, Sandro C. Esteves, Siew May Wang, Damayanthi Durairajanayagam, editors.
• Editors: (Physician), Agarwal, Ashok; Sharma, Rakesh; Gupta, Sajal; Harlev, Avi; Ahmad, Gulfam; Du Plessis, Stefan S; Esteves, Sandro; Wang, Siew May; Durairajanayagam, Damayanthi
• Contents: Foreword; Reference ; Contents; About the Editors; Contributors; Chapter 1: Overview and Sources of Reactive Oxygen Species (ROS) in the Reproductive System; 1.1 Introduction; 1.1.1 Free Radicals; 1.1.1.1 Superoxide Anion (O2−); 1.1.1.2 Hydroxyl Radical (OH); 1.1.2 Oxidation-Reduction (Redox) Reactions; 1.1.2.1 Haber-Weiss Reaction; 1.1.2.2 Electron Transport Chain (ETC); 1.1.3 Reactive Oxygen Species (ROS); 1.1.3.1 Physiological Roles; 1.1.4 Reactive Nitrogen Species (RNS); 1.1.4.1 Physiological Roles; 1.1.5 Sources of ROS in Male Reproductive System; 1.1.5.1 Generation of ROS NADPH OxidasesElectron Leakage in the Mitochondria; 1.1.5.2 Sources of ROS in Seminal Plasma; Immature/Abnormal Spermatozoa; Leukocytes; Varicocele; 1.2 Conclusion; 1.2.1 Sources of ROS in Female Reproductive System; 1.2.2 Steroidogenesis and Ovulation; 1.2.3 Graffian Follicle; 1.2.4 Granulosa Cells and Cumulus Mass Cells; 1.2.5 Follicular Fluid; 1.2.6 Fallopian Tube; 1.2.7 Peritoneal Cavity; 1.2.8 Endometrium; 1.3 Conclusion; 1.3.1 Oxidative Stress (OS); References; Chapter 2: Methods to Measure Reactive Oxygen Species (ROS) and Total Antioxidant Capacity (TAC) in the Reproductive System. 2.1 Introduction2.1.1 Types of Semen Sample Used to Detect ROS; 2.1.2 Measurement of ROS; 2.1.2.1 Nitroblue Tetrazolium Test; 2.1.2.2 Chemiluminescence Assay; 2.1.3 Measurement of DNA Fragmentation; 2.1.3.1 Sperm Chromatin Structure Assay (SCSA); 2.1.3.2 Terminal deoxynucleotidyl Transferees dUTP Nick End Labeling (TUNEL) Assay; 2.1.3.3 Epifluorescence Using Acridine Orange Dye; 2.1.3.4 Comet Assay; 2.1.3.5 Sperm Chromatin Dispersion (SCD) Assay; 2.1.4 Other Methods for Measuring ROS; 2.1.4.1 Measurement of Total Antioxidant Capacity; Colorimetric Analysis; Oxygen Radical Absorbance. Ferric Reducing Ability Assay2.1.4.2 ROS-TAC Score; 2.1.4.3 Measurement of Redox Potential; 2.1.5 Measurement of Lipid Peroxidation; 2.1.5.1 HNE-His Adduct ELISA/HNE Adduct Competitive ELISA; 2.1.5.2 Isprostane (IsoP) Method; 2.1.5.3 TBARS Assay; 2.1.6 Measurement of ROS-Induced Post-Translational Modifications; 2.1.7 Measurement of ROS-Induced Protein Alterations-Proteomic Analysis; 2.1.7.1 Validation of Proteins of Interest; Western Blot Analysis; Immunochemistry; ELISA; 2.2 Conclusion; References; Chapter 3: Physiological Roles of Reactive Oxygen Species (ROS) in the Reproductive System. 3.1 Introduction3.1.1 Physiological Roles of ROS in Male Reproductive System; 3.1.1.1 Spermatogenesis and Sperm Maturation; 3.1.1.2 Sperm Capacitation; 3.1.1.3 Acrosome Reaction; 3.1.1.4 Sperm-oocyte Fusion; 3.2 Conclusion; 3.2.1 Physiological Roles of ROS in the Female Reproductive System; 3.2.1.1 Follicular Development; 3.2.1.2 Ovarian Steroidogenesis; 3.2.1.3 Ovulation; 3.2.1.4 Corpus Luteum; Formation; Luteolysis; 3.2.1.5 Maintenance of Pregnancy; 3.2.1.6 Parturition; 3.3 Conclusion; References; Chapter 4: Negative Effects of Oxidative Stress (OS) on Reproductive System at Cellular Level.
• Publisher Details: Cham, Switzerland : Springer
• Publication Date: 2017
• Extent: 1 online resource (xiv, 190 pages), illustrations (some color)
• Subjects: 612.6; 610; Medicine; Human reproduction -- Molecular aspects; Oxidative stress; Active oxygen -- Physiological effect; MEDICAL -- Physiology; SCIENCE -- Life Sciences -- Human Anatomy & Physiology; Active oxygen -- Physiological effect; Human reproduction -- Molecular aspects; Oxidative stress; Medicine & Public Health; Reproductive Medicine; Oxidative Stress; Embryology; Science -- Life Sciences -- Cytology; Science -- Life Sciences -- Biology -- Developmental Biology; Cellular biology (cytology); Reproductive Medicine; Cytology; Embryology; Health & Fitness -- Diseases -- Genetic; Reproductive medicine; Electronic books; Electronic book
• Languages: English
• ISBNs: 9783319484273; 3319484273
• Related ISBNs: 9783319484259; 3319484257
• Notes: Note: Includes bibliographical references.; Note: Online resource; title from PDF title page (SpringerLink, viewed May 17, 2017).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.