Quantitative decisions in drug development. (2017)

• Record Type: Book
• Further Information: Note: Christy Chuang-Stein, Simon Kirby.
• Authors: Chuang-Stein, Christy; Kirby, Simon, 1959-
• Contents: Clinical Testing of a New Drug.- A Frequentist Decision-making Framework.- Characteristics of a Diagnostic Test.- The Parallel Between Clinical Trials and Diagnostic Tests.- Incorporating Information from Completed Trials in Future Trial Planning.- Choosing Metrics Appropriate for Different Stages of Drug Development.- Designing Proof-of-Concept Trials with Desired Characteristics.- Designing Dose-response Studies with Desired Characteristics.- Designing Confirmatory Trials with Desired Characteristics.- Designing Phase 4 Trials.- Other Metrics That Have Been Proposed to Optimize Drug Development Decisions.- Discounting Prior Results to Account for Selection Bias.- Index.- Appendix.
• Publisher Details: Cham : Springer
• Publication Date: 2017
• Copyright Date: 2017
• Extent: 1 online resource (248 pages)
• Subjects: 615.19; Drug Discovery; Clinical Trials as Topic; Pharmacological Phenomena; Research Design; Models, Theoretical; Statistics as Topic; Drug development; Drug development
• Languages: English
• ISBNs: 9783319460765
• Related ISBNs: 9783319460758
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.