Reviews of physiology, biochemistry and pharmacology. 171 (2016)

• Record Type: Book
• Further Information: Note: Bernd Nilius, Pieter de Tombe, Thomas Gudermann, Reinhard Jahn, Roland Lill, Ole H. Petersen, editors.
• Editors: Nilius, B; Tombe, Pieter de; Gudermann, Thomas; Jahn, Reinhard, 1950-; Lill, Roland; Petersen, O. H (Ole Holger)
• Contents: Curcumin as a MicroRNA Regulator in Cancer: A Review; 1 Curcumin; 2 Anticancer and Cancer Chemo-Preventive Properties of Curcumin; 3 Role of Epigenetics in Cell Homeostasis and Cancer; 4 Role of miRNAs in Cell Homeostasis and Cancer; 5 Search Strategy; 6 Modulation of miRNAs in Different Types of Cancer: The Influence of Curcumin; 6.1 Colon Cancer; 6.2 Pancreatic Cancer; 6.3 Lung Cancer; 6.4 Breast Cancer; 6.5 Prostate Cancer; 6.6 Melanoma; 6.7 Other Types of Cancers; 7 Concluding Remarks; References. Functional Impact of Ryanodine Receptor Oxidation on Intracellular Calcium Regulation in the Heart1 Excitation-Contraction Coupling and SR Ca2+ Cycling; 1.1 Molecular Components of Ca2+ Cycling; 1.2 Ryanodine Receptor Complex; 1.3 Ca2+-Induced Ca2+ Release; 1.4 Luminal Ca2+ and Inter-RyR2 Regulation of CICR; 1.5 SR Ca2+ Leak; 2 SR Ca2+ Cycling in Heart Disease; 2.1 Ischemia/Reperfusion; 2.2 Heart Failure; 3 Oxidative Stress; 3.1 Acute Oxidative Stress in Ischemia/Reperfusion Injury; 3.2 Chronic Oxidative Stress in Heart Failure; 4 Oxidative Posttranslational Modifications of RyR2. 4.1 S-Glutathionylation4.2 S-Nitrosylation; 4.3 Intersubunit Cross-Linking; 5 Conclusion; References; Electromagnetic Fields and Stem Cell Fate: When Physics Meets Biology; 1 Introduction; 2 Natural Endogenous EMFs; 3 Externally Applied EMF; 3.1 Natural Endogenous Fields Are Affected by External EMFs; 3.2 Cell Fate Determinant Factors Are Affected by External EMFs; 3.2.1 Ion Concentration and Transmembrane Potential (TMP); 3.2.2 Intracellular Molecular Mechanisms; 3.2.3 Redox Status and ROS; 3.2.4 Mitochondria; 3.2.5 MT Dynamic Instability; 4 Conclusion; References. The Zebrafish Heart as a Model of Mammalian Cardiac Function1 Introduction to the Zebrafish as a Model; 2 In Vivo Function of the Zebrafish Heart; 3 Whole Heart Measurements; 4 Isolated Cardiomyocytes; 4.1 Electrophysiology; 4.2 Excitation-Contraction (E-C) Coupling; 4.3 Contraction; 5 Molecular Basis of Cardiac Function; 6 Conclusions/Summary; References.
• Publisher Details: Switzerland : Springer
• Publication Date: 2016
• Extent: 1 online resource (v, 136 pages), illustrations
• Subjects: 612; Medicine; Human physiology; Molecular biology; Metabolism -- Disorders; MEDICAL -- Physiology; SCIENCE -- Life Sciences -- Human Anatomy & Physiology; Human physiology; Metabolism -- Disorders; Molecular biology; Medical -- Oncology; Medical -- Cardiology; Oncology; Cardiovascular medicine; Oncology; Cardiology; Physiology; Electronic books; Electronic books
• Languages: English
• ISBNs: 9783319438146
• Related ISBNs: 331943814X; 9783319438139; 3319265636; 9783319265636
• Notes: Note: Includes bibliographical references at the end of each chapters.; Note: Online resource; title from PDF title page (SpringerLink, viewed September 29, 2016).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.