Molecular allergy diagnostics : innovation for a better patient management /: innovation for a better patient management. (2017)

• Record Type: Book
• Further Information: Note: Jörg Kleine-Tebbe, Thilo Jakob, editors.
• Editors: Kleine-Tebbe, Jörg; Jakob, Thilo
• Contents: Foreword 1; Foreword 2; Preface; Molecular Allergology: From Research Topic to Innovative Allergy Diagnosis; Acknowledgments; Contributors; Contents; Part I: Protein Families and Relationships; 1: Introduction to Molecular Allergology: Protein Families, Databases, and Potential Benefits; 1.1 The Era of Molecular Allergology; 1.2 Immediate-Type Allergens and Their Names; 1.3 Sequence and Structure: From T Cell to Antibody (B Cell) Epitopes; 1.4 Protein Families and Relatedness of Type I Allergens; 1.5 Databases for Clinical Practice and Research; 1.6 Potential Use of Single Allergens. 1.6.1 Quantification of Allergens in Extracts1.6.2 Molecular Epidemiology; 1.6.3 Diagnostics with Single Allergens; 1.7 Scope and Limits of Interpretation; 1.8 Immunotherapy and Single Allergens; 1.9 Molecular Allergology Drives Innovation; Conclusions; References; 2: Bet v 1 and its Homologs: Triggers of Tree-Pollen Allergy and Birch Pollen-ƯAssociated Cross-Reactions; 2.1 Introduction; 2.2 Biological Facts and Characteristics; 2.2.1 Allergen Identification; 2.2.2 Family; 2.2.3 Bet v 1 and the Bet v 1 Superfamily; 2.2.4 Physiological Function of Bet v 1; 2.2.5 Characteristics. 2.3 Importance of Bet v 1 and Related Allergens2.3.1 Sources of Bet v 1 and its Biological and Allergological Role; 2.3.2 Prevalence and Distribution of Sensitization; 2.3.3 Bet v 1: A Marker Allergen for Tree (Fagales Order) Pollen Sensitization and IgE Cross-Reactivity to Plant-Derived Foods; 2.3.3.1 Bet v 1 Cross-Reactive Inhalant Allergens; 2.3.3.2 Bet v 1 Cross-Reactive Food Allergens; 2.4 Diagnosis; 2.4.1 Airway Symptoms Caused by Tree Pollen Allergy; 2.4.2 Bet v 1-Associated Cross-Allergies to Plant-Derived Foods; 2.4.3 Added Benefits of Molecular Diagnostics. 2.4.3.1 Advantages of Bet v 1 in Molecular Diagnostics2.4.3.2 Possibilities of Diagnostics Using Bet v 1-Homologous Allergens; 2.5 Therapy and Recommendations; 2.6 Perspectives; 2.7 Conclusions for Clinical Practice; References; 3: The Concept of Pollen Panallergens: Profilins and Polcalcins; 3.1 Introduction; 3.2 Allergen Nomenclature; 3.3 Structure and Function of Profilins; 3.4 Relevance of Profilins; 3.5 Sensitization to Profilins; 3.6 Structure and Function of Polcalcins; 3.7 Relevance of Polcalcins; 3.8 Diagnosis of Relevant Multi-Sensitizations to Pollen. 3.9 Component-Resolved Diagnosis of Panallergen Sensitizations3.10 Clinical Relevance of Panallergens; 3.11 Extract Selection for Allergen Immunotherapy (AIT); 3.12 Conclusions from a Clinical Perspective; References; 4: Stable Plant Food Allergens I: Lipid-Transfer Proteins; 4.1 Introduction; 4.2 Structure of Allergens; 4.3 Biological Function of Allergens; 4.4 Frequency of Sensitization and Geographic Distribution; 4.5 Clinical Relevance; 4.6 IgE Cross-Reactivity Between LTPs; 4.7 Diagnosis by Sensitization Tests with LTPs and LTP-ƯContaining Extracts.
• Publisher Details: Cham, Switzerland : Springer
• Publication Date: 2017
• Extent: 1 online resource
• Subjects: 616.97/075; 610; Medicine; Allergy -- Molecular diagnosis; HEALTH & FITNESS -- Holism; HEALTH & FITNESS -- Reference; MEDICAL -- Alternative Medicine; MEDICAL -- Atlases; MEDICAL -- Essays; MEDICAL -- Family & General Practice; MEDICAL -- Holistic Medicine; MEDICAL -- Osteopathy; Medical -- Dermatology; Medical -- Pediatrics; Medical -- Otorhinolaryngology; Medical -- Pulmonary & Thoracic Medicine; Dermatology; Paediatric medicine; Otorhinolaryngology (ENT); Respiratory medicine; General practice; Allergy; Dermatology; Pediatrics; Otorhinolaryngology; Pneumology; Family medicine; Medical -- Immunology; Allergies; Electronic books
• Languages: English
• ISBNs: 9783319424996; 3319424998
• Related ISBNs: 9783319424989; 331942498X
• Notes: Note: Online resource; title from PDF title page (SpringerLink, viewed May 24, 2017).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.