PI3K-mTOR in cancer and cancer therapy. (2016)

• Record Type: Book
• Further Information: Note: Nandini Dey, Pradip De, Brian Leyland-Jones, editors.
• Editors: Dey, Nandini; De, Pradip; Leyland-Jones, Brian
• Contents: PI3K-Akt-mTOR Signaling in Cancer and Cancer Therapeutics -- Part 1: PI3K-mTOR Pathway in Cancers -- The mTOR Complexes in Cancer Cell Metabolism -- PI3K-AKT-mTOR Pathway Co-operates with the DNA Damage Repair Pathway: Carcinogenesis in Triple Negative Breast Cancers and Beyond -- The AKT-mTOR Signaling Pathway for Drug Response Prediction and Prognostic Signatures -- Resistance to PI3K Pathway Inhibition -- Part 2: PI3K-mTOR Pathway in Cancer Medicine -- Combination Therapies Targeting the PI3K/AKT/mTOR Pathways -- Phospho-Inositol-3-Kinase Activity and Dysregulation in Pediatric Leukemia and Lymphoma -- HER2 Signaling Network in Advanced Breast Cancer: Opportunities for Combination Therapies -- The PI3K-mTOR Pathway in Prostate Cancer: Biological Significance and Therapeutic Opportunities.
• Publisher Details: New York : Humana Press
• Publication Date: 2016
• Extent: 1 online resource (xxiv, 294 pages), color illustrations
• Subjects: 616.99/4; Medicine; Cancer -- Molecular aspects; Cancer -- Treatment; HEALTH & FITNESS / Diseases / General; MEDICAL / Clinical Medicine; MEDICAL / Diseases; MEDICAL / Evidence-Based Medicine; MEDICAL / Internal Medicine; Cancer -- Molecular aspects; Cancer -- Treatment; Neoplasms -- drug therapy; Antineoplastic Agents -- therapeutic use; Phosphatidylinositol 3-Kinase -- metabolism; Signal Transduction -- drug effects; TOR Serine-Threonine Kinases -- metabolism; Science -- Life Sciences -- Biology -- Molecular Biology; Medical -- Pharmacology; Medical research; Pharmacology; Oncology; Drug interactions; Medical -- Oncology; Oncology; Electronic books; Electronic books
• Languages: English
• ISBNs: 9783319342115; 3319342118; 3319342096; 9783319342092
• Related ISBNs: 9783319342092
• Notes: Note: Includes bibliographical references at the end of each chapters and index.; Note: Online resource; title from PDF title page (SpringerLink, viewed June 20, 2016).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.