Applications of mass spectrometry in microbiology : from strain characterization to rapid screening for antibiotic resistance /: from strain characterization to rapid screening for antibiotic resistance. (2016)

• Record Type: Book
• Further Information: Note: Plamen Demirev, Todd R. Sandrin, editors.
• Editors: Demirev, Plamen; Sandrin, Todd R
• Contents: Introduction -- SECTION I. METHODOLOGY AND TECHNIQUES.- Methods and instrumentation in mass spectrometry for the differentiation of closely related microorganisms.- Sample preparation methods for the rapid MS analysis of microorganisms.- Advantages offered by proteomic strategies for rapid biodetection.- Bottom Up Proteomics Methods for Strain-Level Typing and Identification of Bacteria.- Maximizing the taxonomic resolution of MALDI-TOF-MS-based approaches to bacterial characterization: From culture conditions through data analysis -- SECTION II. SUB-SPECIES DISCRIMINATION.- Modulation of the Discriminatory Power of MALDI-TOF MS Profiling for Distinguishing between Closely Related Bacterial Strains.- Discriminatory Power of MALDI-TOF Mass Spectrometry for Phylogenetically Closely Related Microbial Strains.- MALDI-TOF MS as a novel tool for dereplication and characterization of microbiota in bacterial diversity studies.- Bacterial Identification at the Serovar level by Top-down Mass Spectrometry -- SECTION III. DRUG RESISTANCE MONITORING AND ASSAYS.- Rapid profiling of human pathogenic bacteria and antibiotic resistance employing specific tryptic peptides as biomarkers.- Detection of ?-lactamases and their activity using MALDI-TOF MS.- Stable-isotope based strategies for rapid determination of drug resistance by mass spectrometry.
• Publisher Details: Cham : Springer
• Publication Date: 2016
• Extent: 1 online resource (viii, 336 pages), illustrations (some color)
• Subjects: 543/.65; Chemistry; Mass spectrometry; Microbiology; Microbiological chemistry; SCIENCE / Chemistry / Analytic; Mass spectrometry; Microbiological chemistry; Microbiology; Mass Spectrometry; Microbiology; Chemistry; Mass Spectrometry; Applied Microbiology; Epidemiology; Drug Resistance; Science -- Biotechnology; Medical -- Epidemiology; Medical -- Pharmacology; Microbiology (non-medical); Epidemiology & medical statistics; Pharmacology; Epidemiology; Drug interactions; Science -- Spectroscopy & Spectrum Analysis; Spectrum analysis, spectrochemistry, mass spectrometry; Electronic books; Electronic books
• Languages: English
• ISBNs: 9783319260709; 3319260707
• Related ISBNs: 9783319260686; 3319260685
• Notes: Note: Online resource; title from PDF title page (SpringerLink, viewed January 20, 2016).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.