Organic cation transporters : integration of physiology, pathology, and pharmacology /: integration of physiology, pathology, and pharmacology. ([2016])

• Record Type: Book
• Further Information: Note: Giuliano Ciarimboli, Sophie Gautron, Eberhard Schlatter, editors.
• Editors: Ciarimboli, Giuliano, 1962-; Gautron, Sophie; Schlatter, Eberhard
• Contents: Introduction to the cellular transport of organic cations -- Functional properties of organic cation transporter OCT1, binding of substrates and inhibitors, and presumed transport mechanism -- Pharmacological and toxicological significance of the organic cation transporters OCT and MATE: Drug disposition, interaction and toxicity -- Genetic variability in organic cation transporters: pathophysiological manifestations and consequences for drug pharmacokinetics and efficacy -- Physiological and pathological regulation of transporters for organic cations -- Endocrine and metabolic regulation of transporters for organic cations -- Organic cation transporters (OCTs) as modulators of behavior and mood -- Organic cation transporters as modulators of neurodegeneration and neuroprotection -- Translational relevance of animal models for the study of organic cation transporter function -- Role of transporters for organic cations in plants for environmental cycling of pharmaceutical residues.
• Publisher Details: Cham : Springer
• Publication Date: 2016
• Copyright Date: 2016
• Extent: 1 online resource (xv, 264 pages), illustrations (some color)
• Subjects: 572/.696; Medicine; Carrier proteins; Cations; SCIENCE -- Life Sciences -- Biochemistry; Carrier proteins; Cations; Membrane Transport Proteins -- physiology; Biological Transport -- physiology; Biomedicine; Human Physiology; Pharmacology/Toxicology; Pathology; Medical -- Pharmacology; Medical -- Pathology; Pharmacology; Pathology; Human physiology; Toxicology; Pathology; Medical -- Physiology; Physiology; Electronic books
• Languages: English
• ISBNs: 9783319237930; 3319237934; 3319237926; 9783319237923
• Related ISBNs: 9783319237923
• Notes: Note: Includes bibliographical references and index.; Note: Online resource; title from PDF title page (SpringerLink, viewed December 28, 2015).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.