Genotoxicity and carcinogenicity testing of pharmaceuticals. ([2015])

• Record Type: Book
• Further Information: Note: Michael J. Graziano, David Jacobson-Kram, editors.
• Editors: Graziano, Michael J; Jacobson-Kram, David, 1949-
• Contents: Introduction -- History and Current Regulatory Requirements -- Genotoxicity Testing of API and Impurities -- New Emerging Genotoxicity Tests -- Carcinogenicity Testing of Small Molecules -- Alternatives to the 2-Year Rodent Studies -- Addressing Positive Findings in Carcinogenicity Studies -- Investigating Tumor Signals in Clinical Trials -- Tumor Promoters -- Carcinogenicity Testing of Biologics -- In Silico Predictive Tests.
• Publisher Details: Cham New York : Springer International Publishing
• Publication Date: 2015
• Copyright Date: 2015
• Extent: 1 online resource (x, 206 pages)
• Subjects: 616.99/4071; Medicine; Genetic toxicology; Carcinogenicity testing; HEALTH & FITNESS -- Diseases -- General; MEDICAL -- Clinical Medicine; MEDICAL -- Diseases; MEDICAL -- Evidence-Based Medicine; MEDICAL -- Internal Medicine; Carcinogenicity testing; Genetic toxicology; Mutagenicity Tests; Biomedicine; Cancer Research; Pharmaceutical Sciences/Technology; Medical -- Pharmacy; Pharmaceutical technology; Oncology; Pharmaceutical technology; Medical -- Oncology; Oncology; Electronic books
• Languages: English
• ISBNs: 9783319220840; 3319220845
• Related ISBNs: 9783319220833; 3319220837; 9783319220833
• Notes: Note: Includes bibliographical references and index.; Note: Vendor-supplied metadata.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.