Life extension : lessons from drosophila /: lessons from drosophila. ([2015])

• Record Type: Book
• Further Information: Note: Alexander M. Vaiserman, Alexey A. Moskalev, Elena G. Pasyukova, editors.
• Editors: Vaiserman, Alexander; Moskalev, A. A (Alekseĭ Aleksandrovich), 1976-; Pasyukova, Elena G
• Contents: Preface -- SECTION I: Genetic regulation of longevity -- Mutations and quantitative genetic variation: lessons from Drosophila -- Modulation of Drosophila lifespan by neuronal genes -- Life span, stress resistance and age-dependent transcriptome dynamics in fruit flies with constitutive and conditional overexpression of GADD45 -- Superoxide dismutase over-expression and the mitochondrial unfolded protein response -- Effect of Wolbachia infection on aging and longevity-associated genes in Drosophila -- SECTION II: Drosophila models for aging-associated diseases -- Skeletal muscle homeostasis and aging -- Drosophila models of cardiac disease -- Genetic modulation of cardiac functional aging -- Functional links between circadian clocks, redox state and aging in Drosophila -- Drosophila models in therapeutic drug discovery -- SECTION III: Life-extending treatments -- Phytochemicals with lifespan extension effect in Drosophila -- Life extension in Drosophila by inhibitors of histone deacetylases -- Drosophila healthspan extension using dietary manipulation -- The effect of the artificial atmosphere on the flies' longevity -- Effects of several mild stresses applied in adults on aging and longevity -- Life extension via stage-specific drug interventions in Drosophila -- Index.
• Publisher Details: Cham : Springer
• Publication Date: 2015
• Copyright Date: 2015
• Extent: 1 online resource (viii, 353 pages), illustrations (some color)
• Subjects: 612.68; Medicine; Life expectancy; Longevity; Fruit-flies; MEDICAL -- Physiology; SCIENCE -- Life Sciences -- Human Anatomy & Physiology; Fruit-flies; Life expectancy; Longevity; Biomedicine; Biomedicine general; Animal Genetics and Genomics; Geriatrics/Gerontology; Science -- Life Sciences -- Zoology -- General; Medical -- Geriatrics; Animal reproduction; Geriatric medicine; Animal genetics; Geriatrics; Medical -- General; Medical research; Electronic books
• Languages: English
• ISBNs: 9783319183268; 3319183265
• Related ISBNs: 3319183257; 9783319183251; 9783319183251
• Notes: Note: Includes bibliographical references and index.; Note: Online resource; title from PDF title page (EBSCO, viewed June 16, 2015).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.