Protein kinase CK2 cellular function in normal and disease states. ([2015])

• Record Type: Book
• Further Information: Note: Khalil Ahmed, Olaf-Georg Issinger, Ryszard Szyszka, editors.
• Editors: Ahmed, Khalil, 1934-; Issinger, O. G; Szyszka, Ryszard
• Contents: 1. CK2 Suppression of Apoptosis -- 2. Structural Determinants of CK2 Regulation -- 3. Targeting Protein Kinase: CK2 Suppresses Pro-Survival Signaling Pathways and Growth of Gliobastoma -- 4. The Roles of CK2 in Drosophila Neurogenesis -- 5. Targeting the CK2 Subunit Interface: Challenge and Usefulness -- 6. CK2 in Wnt/Ý-catenin signaling and embryo development -- 7. Defective expression of CK2Ý promotes EMT and stemness properties both required for breast cancer progression -- 8. Chemical Biology Approaches to Identify CK2 Substrates and Perform Unbiased Evaluation of CK2 Inhibitors -- 9. Development of Screening Systems and Identification of Novel Potent Inhibitors of Human Protein Kinase CK2 -- 10. Protein Kinase CK2: At the Crossroad of Regulatory Cellular Pathways -- 11. Functional Regulation of DYRK Family Protein Kinases by Cellular Binding Partners -- 12. Regulation of CK2 in pancreatic Ý cells -- 13. Recent impressions from the configurational and conformational space captured by protein kinase CK2 -- 14. Role of CK2 in Plant Responses to Abiotic Stress -- 15. 2Genuine3 Casein Kinase: The False Sister of CK2: Phosphorylates-Secreted Proteins -- 16. CK2: -- A Novel Player in L-DOPA induced dyskinesia in a mouse model of Parkinson's disease -- 17. CK2 function in the regulation of Akt Pathway: new findings and perspectives -- 18. CK2 structure from yeast to human -- 19. Cellular zinc signaling is triggered by CK2 -- 20. A Nanomedicine Approach to Targeting CK2 for Cancer therapy -- 21. Bisubstrate approach for construction of high-affinity inhibitors and optical probes for protein kinase CK2.
• Publisher Details: Cham Heidelberg : Springer
• Publication Date: 2015
• Copyright Date: 2015
• Extent: 1 online resource
• Subjects: 612/.015756; Medicine; Protein kinase CK2; MEDICAL -- Physiology; SCIENCE -- Life Sciences -- Human Anatomy & Physiology; Protein kinase CK2; Casein Kinase II -- physiology; Biomedicine; Cancer Research; Protein Science; Apoptosis; Science -- Life Sciences -- Biochemistry; Science -- Life Sciences -- Cytology; Proteins; Cellular biology (cytology); Oncology; Biochemistry; Cytology; Medical -- Oncology; Oncology; Electronic books
• Languages: English
• ISBNs: 9783319145440; 3319145444; 3319145436; 9783319145433
• Related ISBNs: 9783319145433
• Notes: Note: Includes bibliographical references and index.; Note: Vendor-supplied metadata.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.