Lipids and skin health. ([2015])

• Record Type: Book
• Further Information: Note: Apostolos Pappas, editor.
• Editors: Pappas, Apostolos
• Contents: Contributors; Part I; Editor's Introduction: Skin Lipids; Chapter 1; Skin Lipids: An Introduction and Their Importance; Part II; Skin Basics; Chapter 2; Skin Basics Structure and Function; Introduction; Functional Aspects of Skin in Health; Structural Organization of the Mammalian Skin; Epidermis; Diverse and Interdependent Barriers in Epidermis; The Dermal-Epidermal Junction (DEJ) or the Basement Membrane Zone (BMZ); The Dermis; Collagen; Elastin; Glycosaminoglycans (GAG); Fibroblasts; Other Components; Skin Appendages; Hypodermis; Summary of Skin Functions; References; Chapter 3. Skin Barrier, Structure, and PropertiesIntroduction; History; Skin Lipid Composition and Phase State; Molecular Structure Determination Directly In Situ; The Procedure; CEMOVIS; Modeling and Simulation of the Horny Layer Lipid organization; Skin Lipid Structure; Skin Lipid Formation; Skin Lipid Function; Summary; References; Chapter 4; Polyunsaturated Fatty Acid Oxygenated Metabolites in Skin; Introduction; Cyclooxygenase-Derived Lipid Mediators; Lipoxygenase-Derived Lipid Mediators; Cytochrome P450-Derived Lipid Mediators; Non-enzymatically Produced Oxidised Lipid Mediators. Bioactivities of Oxidised Lipid Mediators and Role in Inflammatory Skin DiseaseBioactivity of Cutaneous Prostanoids; Bioactivity of Cutaneous Hydroxy and Epoxy Fatty Acids; References; Part III; Epidermal Lipids; Chapter 5; Skin Ceramides; Introduction; Biosynthetic Pathways; Structures, Proportions, and Properties; Catabolism; References; Chapter 6; Cholesterol Metabolism in the Epidermis; Introduction; Unraveling the Significance of Cholesterol for Skin Permeability Barrier Function; Effects of Aging; Cholesterol Sulfate; Role of Cholesterol Sulfate in Keratinocyte Differentiation. Steroid SulfataseRole of Cholesterol Sulfate in Desquamation; Role of Cholesterol Sulfate in Permeability Function; Conclusion; References; Chapter 7; Nuclear Hormone Receptors and Epidermal Differentiation; Introduction; Keratinocyte Differentiation; Transcriptional Regulation of Keratinocyte Differentiation: Nuclear Hormone Receptors; Vitamin D Receptor (VDR); Retinoic Acid Receptors (RARs) and Retinoid X Receptors (RXRs); Peroxisome Proliferator-Activated Receptors (PPARs); Additional Remarks; Summary; References; Part IV; Sebaceous Lipids; Chapter 8; The Brain of the Skin: Sebaceous Gland. Introduction: The Birth of NeurodermatologyHormone Receptors in Human Sebaceous Glands and Their Biological Activity; Peptide Hormone and Neurotransmitter Receptors; Nuclear Receptors; Activation of the HPA-Like Skin Axis in Sebaceous Glands; Androgens and Sebaceous Gland Development, Cell Differentiation, and Lipogenesis; Signaling and Metabolic Pathways Operative in Hormonally Aged Sebocytes In Vitro; Conclusions; References; Chapter 9; Sebaceous Lipids; Introduction; Sebaceous Lipids and Their Uniqueness; a) Sapienic Acid; b) Wax Esters; c) Squalene.
• Publisher Details: Cham : Springer
• Publication Date: 2015
• Copyright Date: 2015
• Extent: 1 online resource (x, 359 pages), illustrations (some color)
• Subjects: 612.397; Life sciences; Lipids; Skin; MEDICAL -- Physiology; SCIENCE -- Life Sciences -- Human Anatomy & Physiology; Lipids; Skin; Skin -- chemistry; Skin Physiological Phenomena; Lipids -- physiology; Life Sciences; Lipidology; Dermatology; Nutrition; Food Science; Medical -- Dermatology; Science -- Life Sciences -- Biochemistry; Technology & Engineering -- Food Science; Dermatology; Biochemistry; Food & beverage technology; Dermatology; Nutrition; Food science; Lipids; Electronic books
• Languages: English
• ISBNs: 9783319099439; 3319099434; 3319099426; 9783319099422
• Related ISBNs: 9783319099422
• Notes: Note: Includes bibliographical references and index.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.