Leveraging Biomedical and Healthcare Data : Semantics, Analytics and Knowledge /: Semantics, Analytics and Knowledge. (2018)

• Record Type: Book
• Further Information: Note: Edited by Firas Kobeissy [and 3 others].
• Editors: Kobeissy, Firas; Wang, Kevin; Zaraket, Fadi A; Alawieh, Ali
• Contents: Front Cover; Leveraging Biomedical and Healthcare Data: Semantics, Analytics and Knowledge; Copyright; Dedication; Contents; Contributors; Foreword I; Foreword II; Preface; Acknowledgments; Chapter 1: Comprehensive Workflow for Integrative Transcriptomics Meta-Analysis; 1. Introduction; 2. Data Preparation; 2.1. Data Download; 2.2. Quality Control; 2.2.1. Single-Array Metrics; 2.2.2. Multiarray Metrics; 2.3. Data Preprocessing; 2.3.1. Background Correction; 2.3.2. Normalization; 2.3.3. Summarization; 2.3.4. Comparison Between Different Procedures 2.4. Batch Effect: A Special Concern During Data Integration3. Crossplatform Integration; 4. Conclusion; References; Chapter 2: Proteomics and Protein Interaction in Molecular Cell Signaling Pathways; 1. Introduction; 2. Experimental Techniques; 3. Computational Methods; 3.1. Sequences Databases and Analysis; 3.2. Protein Feature Prediction Using Protein Sequence; 3.3. Structure Databases and Analysis; 3.4. Protein Families; 3.5. Interactions, Pathways, and System Biology; 3.6. Posttranslational Modifications; 4. Conclusion; References Chapter 3: Understanding Specialized Ribosomal Protein Functions and Associated Ribosomopathies by Navigating Across Sequ ...1. Introduction; 2. RPs and Diseases; 2.1. Ribosomopathies; 2.2. Cancer; 3. Specialized Functions of RPs; 3.1. RP-Mediated Translational Control of Distinct mRNAs, Through Interaction With IRES cis-Regulatory Elements; 3.2. Posttranslational Modifications (PTMs) of RPs; 3.3. RP Gene Expression; 3.4. RP Paralogs; 3.5. Differential Subcellular Stoichiometry of RPs; 4. Exploring RP Roles in Health and Disease by Navigating Bioinformatics Resources; 4.1. RP Nomenclature 4.2. Comparison of Human and Mouse RPs Reveals a Range of Conservation Levels5. Conclusions and Future Directions; References; Chapter 4: Big Data, Artificial Intelligence, and Machine Learning in Neurotrauma; 1. Introduction; 2. Big Data: Characteristics, Definitions, and Examples; 3. Traumatic Brain Injury (TBI); 4. Big Data in TBI; 5. Machine Learning; 6. Artificial Intelligence; 7. Text Mining; 8. Examples of Using BD Approaches in TBI Research; 9. Imaging; 10. Biochemical Markers; 11. Legacy Data; 12. Future of Big Data in TBI; References Chapter 5: Artificial Intelligence Integration for Neurodegenerative Disorders1. Introduction; 2. Wearables and ML-Based Therapeutics; 3. Neurodegenerative Therapeutics Through AI; 3.1. Parkinson's Disease; 3.2. Seizures and Epilepsy; 3.3. Alzheimer's Disease; 3.4. Amyotrophic Lateral Sclerosis; 3.5. Stroke and Spinal Cord Injury; 4. AI-Based Clinical Decision-Making; 5. Limitations and Future Perspectives; References; Chapter 6: Robust Detection of Epilepsy Using Weighted-Permutation Entropy: Methods and Analysis; 1. Introduction; 1.1. Background; 1.2. Approach; 2. Computational Details
• Publisher Details: London : Elsevier Ltd Academic Press
• Publication Date: 2018
• Extent: 1 online resource
• Subjects: 610.285; Medical care -- Data processing; Proteomics; Protein-protein interactions; Nervous system -- Degeneration; HEALTH & FITNESS / Holism; HEALTH & FITNESS / Reference; MEDICAL / Alternative Medicine; MEDICAL / Atlases; MEDICAL / Essays; MEDICAL / Family & General Practice; MEDICAL / Holistic Medicine; MEDICAL / Osteopathy; Electronic books
• Languages: English
• ISBNs: 9780128095614
• Related ISBNs: 012809561X; 9780128095560
• Notes: Note: Online resource; title from PDF title page (EBSCO, viewed November 28, 2018).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.